Synfacts 2011(3): 0336-0336  
DOI: 10.1055/s-0030-1259467
Polymer-Supported Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Arylation of Indoles with Supported Palladium Nanoparticles

Contributor(s): Yasuhiro Uozumi, Noboru Kobayashi
L. Wang, W.-b. Yi, C. Cai*
Nanjing University of Science and Technology, P. R. of China
Further Information

Publication History

Publication Date:
16 February 2011 (online)


Fluorous silica gel (FSG) supported palladium nanoparticles (Pd-1/FSG) were prepared via immobilization of perfluoro chain functionalized benzene 1 stabilized palladium nanoparticles (Pd-1) on FSG by fluorous-fluorous interactions. Pd-1/FSG catalyzed the arylation of indoles with aryl halides to give the corresponding 2-arylindoles in up to 92% yield (19 examples).