Synfacts 2011(3): 0260-0260  
DOI: 10.1055/s-0030-1259573
Synthesis of Heterocycles
© Georg Thieme Verlag Stuttgart ˙ New York

Multicomponent Aza-Diels-Alder Synthesis of Phenanthrolines and Pyranoquinolines

Contributor(s): Victor Snieckus, Johnathan Board
K. C. Majumdar*, S. Ponra, D. Ghosh, A. Taher
University of Kalyani, India
Further Information

Publication History

Publication Date:
16 February 2011 (online)


Reported is the multicomponent ­reaction of aromatic aldehydes and alkynes with 6-amino coumarins or 6-amino quinolones to give the tricyclic products shown. This reaction is proposed to proceed first through formation of the requisite imine, followed by an aza-Diels-Alder ­reaction. For optimum yields, a slight excess of the amine and the aldehyde with respect to the alkyne is required.