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Polysequential Synthesis of 2-Azaanthra-cenes from Ethynylbenzenes
J. Cao, X. Yang, X. Hua, Y. Deng, G. Lai*
Hangzhou Normal University, P. R. of China
18 March 2011 (online)
A sequence of Sonogashira coupling, alkynyl imine-allenyl imine isomerization, aza-Diels-Alder, and elimination-aromatization reactions is reported. Thus, 1,6-diynes and imidoyl chlorides are converted into substituted 2-azaanthracenes in high yields.