Synfacts 2011(4): 0432-0432  
DOI: 10.1055/s-0030-1259609
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Palladium-Catalyzed Cross-Coupling of Tosylhydrazones and Aryl Nonaflates

Contributor(s): Paul Knochel, Thomas Kunz
J. Barluenga*, L. Florentino, F. Aznar, C. Valdés*
Universidad de Oviedo, Spain
Further Information

Publication History

Publication Date:
18 March 2011 (online)


The authors report a palladium-­catalyzed cross-coupling reaction of tosylhydrazones and aryl nonaflates. The hydrazones are readily available from carbonyl compounds. The reaction does not require stoichiometric amounts of organometallic reagents and allows an efficient synthesis of di-, tri-, and tetrasubstituted aryl alkenes.