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Synthesis of Sintokamides A, B and E
Z. Gu, A. Zakarian*
University of California at Santa Barbara, USA
18 March 2011 (online)
Sintokamides A-E were isolated from the marine sponge Dysidea sp. and represent a rare class of halogenated natural products. Sintokamides B and E were synthesized using the trichloromethyl derivative of J and l-leucine methyl ester hydrochloride instead of J, respectively (not shown).