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Synfacts 2011(9): 0997-0997  
DOI: 10.1055/s-0030-1260889
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Rh-Catalyzed Asymmetric Addition of Trifluoroborates to Sulfonylketimines

Contributor(s): Paul Knochel, Andreas J. Wagner
R. Shintani*, M. Takeda, Y.-T. Soh, T. Ito, T. Hayashi*
Kyoto University, Japan
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Publication History

Publication Date:
19 August 2011 (online)

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Significance

Easily accessible potassium orga­notrifluoroborates undergo a rhodium-catalyzed asymmetric addition to both N-tosyl and N-nosyl ketimines. The use of a chiral bicyclooctadiene-based ligand allows high enantiomeric excess in the product formation.