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Suzuki-Miyaura Coupling in Water Using an NHC-Pd Polymer
B. Karimi*, P. F. Akhavan
Institute for Advanced Studies in Basic Sciences, Gava Zang, Iran
19 August 2011 (online)
A water-soluble NHC-Pd polymer 3 was prepared by the reaction of 1 with TEG-Br in the presence of NaH followed by treatment with Pd(OAc)2 (eq. 1). The NHC-Pd polymer 3 catalyzed the Suzuki-Miyaura coupling of aryl bromides or aryl chlorides with arylboronic acids in water to give the corresponding biaryls in 69-93% yield (21 examples, eq. 2).