Synlett 2012(1): 120-122  
DOI: 10.1055/s-0031-1289910
LETTER
© Georg Thieme Verlag Stuttgart ˙ New York

Synthesis of Complex Glycosylated Carboranes for BNCT

Federica Campo, Matteo Mossotti, Luigi Panza*
Università degli Studi del Piemonte Orientale ‘Amedeo Avogadro’, Dipartimento di Scienze Chimiche, Alimentari, Farmaceutiche e Farmacologiche, via Bovio 6, 28100 Novara, Italy
Fax: +39(0321)375621; e-Mail: luigi.panza@pharm.unipmn.it;
Further Information

Publication History

Received 22 August
Publication Date:
28 November 2011 (online)

Abstract

An efficient strategy for the preparation of carboranyl derivatives from a common intermediate containing a sugar moiety functionalized with an azido group is described. Such compounds should allow either the conjugation with peptides or proteins for an improved delivery of the products, or the monitoring of the biodistribution profile.

    References and Notes

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7

All new compounds gave satisfactory elemental analysis and spectroscopic data (see Supporting Information).