Am J Perinatol 2013; 30(01): 001-004
DOI: 10.1055/s-0032-1322511
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

The Role of Massive Transfusion Protocols in Obstetrics

Authors

  • Luis D. Pacheco

    1   Division of Maternal–Fetal Medicine, Department of Obstetrics and Gynecology, The University of Texas Medical Branch, Galveston, Texas
    2   Division of Surgical Critical Care, Department of Anesthesiology, The University of Texas Medical Branch, Galveston, Texas
  • George R. Saade

    1   Division of Maternal–Fetal Medicine, Department of Obstetrics and Gynecology, The University of Texas Medical Branch, Galveston, Texas
  • Maged M. Costantine

    1   Division of Maternal–Fetal Medicine, Department of Obstetrics and Gynecology, The University of Texas Medical Branch, Galveston, Texas
  • Steven L. Clark

    3   Women and Newborns Clinical Program, Hospital Corporation of America, Salt Lake City, Utah
  • Gary D.V. Hankins

    1   Division of Maternal–Fetal Medicine, Department of Obstetrics and Gynecology, The University of Texas Medical Branch, Galveston, Texas
Weitere Informationen

Publikationsverlauf

30. Januar 2012

16. März 2012

Publikationsdatum:
26. Juli 2012 (online)

Preview

Abstract

Obstetric hemorrhage is a leading cause of maternal mortality worldwide. New concepts involving the pathophysiology of hemorrhage have been described and include early activation of both the protein C and fibrinolytic pathways. New tendencies in hemorrhage treatment include the use of hemostatic resuscitation. Massive transfusion protocols involve the early utilization of blood products and limit the traditional approach of early massive crystalloid based resuscitation. The evidence behind hemostatic resuscitation is still limited.