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Synlett 2015; 26(03): 275-284
DOI: 10.1055/s-0034-1379426
DOI: 10.1055/s-0034-1379426
synpacts
Towards Tris(diimine)–Ruthenium(II) and Bis(quinoline)–Re(I)(CO)3 Complexes as Photoactivated Anticancer Drug Candidates
Autoren
Weitere Informationen
Publikationsverlauf
Received: 19. August 2014
Accepted after revision: 14. Oktober 2014
Publikationsdatum:
09. Januar 2015 (online)
Abstract
The clinical success of cisplatin continues to inspire the development of metal-based anticancer drug candidates. This article is meant to present the current state-of-the-art and science of ruthenium(II)- and rhenium(I)-based anticancer drug candidates born out of our work in this field. Our recent efforts to elicit photoactivation of intact (organo)metallic anticancer drug candidates as a promising way for commanding their activity within cancer cells are also briefly summarized.
1 Introduction
2 Ruthenium(II) Complexes
3 Rhenium(I) Complexes
4 Concluding Remarks
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