J Pediatr Intensive Care 2015; 04(02): 073-078
DOI: 10.1055/s-0035-1556749
Review Article
Georg Thieme Verlag KG Stuttgart · New York

Pediatric Withdrawal Identification and Management

Katherine T. Whelan
1   Division of Cardiac Intensive Care, Department of Cardiovascular/Critical Care Nursing, Boston Children's Hospital, Boston, Massachusetts, United States
,
Maura K. Heckmann
2   Division of Critical Care, Department of Anesthesia, Perioperative and Pain Medicine, Boston Children's Hospital, Boston, Massachusetts, United States
,
Patricia A. Lincoln
3   Department of Cardiovascular/Critical Care Nursing, Cardiovascular Intensive Care Unit, Boston Children's Hospital, Boston, Massachusetts, United States
,
Susan M. Hamilton
4   Department of Cardiovascular/Critical Care Nursing, Medical Surgical Intensive Care Unit, Boston Children's Hospital, Boston, Massachusetts, United States
› Author Affiliations
Further Information

Publication History

01 November 2014

20 November 2014

Publication Date:
28 August 2015 (online)

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Abstract

Sedation administered by continuous intravenous infusion is commonly used in the pediatric intensive care unit to facilitate and maintain safe care of children during critical illness. Prolonged use of sedatives, including opioids, benzodiazepines, and potentially other adjunctive agents, is known to cause withdrawal symptoms when they are stopped abruptly or weaned quickly. In this review, the common signs and symptoms of opioid, benzodiazepine, and dexmedetomidine withdrawal will be discussed. Current tools used to measure withdrawal objectively, as well as withdrawal prevention and management strategies, will be discussed.