J Pediatr Intensive Care 2015; 04(03): 156-161
DOI: 10.1055/s-0035-1559825
Original Article
Georg Thieme Verlag KG Stuttgart · New York

Maternal Morbidities and Occurrence of Intraventricular Hemorrhage in Preterm Infants

Arash Bordbar
1   Department of Neonatology, Akbarabadi Hospital, Iran University of Medical Sciences, Tehran, Iran
,
Mahgol Farjadnia
1   Department of Neonatology, Akbarabadi Hospital, Iran University of Medical Sciences, Tehran, Iran
› Author Affiliations
Further Information

Publication History

11 December 2014

24 January 2015

Publication Date:
07 August 2015 (online)

Abstract

Intraventricular hemorrhage (IVH) is one of the most serious neurological morbidities in preterm infants. Several prenatal, intrapartum, and neonatal risk factors have been detected in different studies. However, maternal conditions that may render the neonates to IVH have been the subject of very few studies. Preterm infants with and without IVH were included in the study, and maternal obstetrics and general health clinical files were reviewed for any kind of morbidity. Data were then analyzed with statistical software to assess the association between maternal conditions and IVH. A total of 115 neonates with IVH and 120 infants without IVH were recruited. Among all maternal conditions, prolonged rupture of membrane (p = 0.00), laparoscopic surgery for infertility (p = 0.001), and in vitro fertilization (IVF) (p = 0.00) increased the risk of IVH in neonates significantly. IVF remained strongly associated with IVH even after controlling for confounding variables (odds ratio: 9.75; confidence interval: 2.66–35.75; p = 0.001). Based on our findings, prolonged rupture of membrane and IVF were maternal conditions that increased the risk of IVH. Laparoscopic surgery for infertility was also associated with an increased risk of IVH.

 
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