DOI: 10.1055/s-0036-1589105
© Georg Thieme Verlag Stuttgart · New York

One-Pot Michael Addition/Radical Cyclization Reaction of N-Acryloyl Indoles

Lauren C. Irwin, Michael A. Kerr*
  • Department of Chemistry, The University of Western Ontario, London, ON, N6A 5B7, Canada   Email:
We are grateful to the Natural Sciences and Engineering Research Council of Canada (NSERC) for generous funding of this research. LCI is a recipient of an OGS scholarship.
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Publication History

Received: 29 July 2017

Accepted after revision: 11 August 2017

Publication Date:
21 September 2017 (eFirst)


From N-acryloyl indoles, ten examples of 1,2-annulated ­indole products were generated in a one-pot procedure via a Michael addition and radical cyclization mediated by Mn(OAc)3.

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