DOI: 10.1055/s-0036-1590978
© Georg Thieme Verlag Stuttgart · New York

Synthesis of N-Arylsulfonamides by a Copper-Catalyzed Reaction of Chloramine-T and Arylboronic Acids at Room Temperature

Banlai Ouyang*a, Deming Liua, Kejian Xiaa, Yanxia Zhenga, Hongxin Meia, Guanyinsheng Qiu*b
  • aDepartment of Chemistry, Nanchang Normal University, 889 Ruixiang Road, Nanchang 330032, P. R. of China   Email:
  • bCollege of Biological, Chemical Science and Engineering, Jiaxing University, 118 Jiahang Road, Jiaxing 314001, P. R. of China   Email:
This work was supported by the National Natural Science Foundation of China (No. 21502069), the Science and Technology Project of the Education Department of Jiangxi Province (No. GJJ161236), and the Key Discipline Project of Nanchang Normal University (No. NSXK20141003).
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Publication History

Received: 14 June 2017

Accepted after revision: 04 August 2017

Publication Date:
29 August 2017 (eFirst)


A copper-catalyzed Chan–Lam-coupling-like reaction of a (het)arylboronic acid and chloramine-T (or a related compound) has been developed for the synthesis of N-arylsulfonamides at room temperature in moderate to good yields, with good tolerance of functional groups. In this process, it is believed that chloramine-T serves as an electrophile.

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