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CC BY ND NC 4.0 · SynOpen 2018; 02(02): 0138-0144
DOI: 10.1055/s-0036-1591572
DOI: 10.1055/s-0036-1591572
paper
Efficient Syntheses of Diverse N-Heterocycles: The Molybdenum(VI)-Catalyzed Reductive Cyclization of Nitroarenes using Pinacol as a Deoxygenating Agent
C.C.M. acknowledges Science and Engineering Research Board (SERB), New Delhi and NIT Manipur for the financial support in the form of research grant (ECR/2016/000337). R.G., N.V., D.K. and A.K.K. are grateful to the Ministry of Human Resource and Development (MHRD), New Delhi for Fellowship support.Further Information
Publication History
Received: 31 January 2018
Accepted after revision: 05 April 2018
Publication Date:
09 May 2018 (online)
Abstract
Molybdenum(VI)-catalyzed domino reductive cyclization of nitroarenes has been devised for the syntheses of 1,4-benzoxazines and 1,4-benzothiazines in the presence of pinacol as deoxygenating agent. The scope of the described method was further extended to the syntheses of the rarely explored scaffolds, 1-hydroxyphenazines and quinoxalines. The present method avoids the use of hazardous deoxygenating agents and operates under solvent-free conditions.
Key words
N-heterocycles - domino reaction - reductive cyclization - nitroarenes - dioxo-Mo(VI) complex - pinacolSupporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0036-1591572.
- Supporting Information
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