First Total Synthesis of Cryptopyranmoscatone A3 and Crypto­pyranmoscatone B4

Abstract

The first total synthesis of cryptopyranmoscatones A3 and B4 has been accomplished from d-ribose or but-3-ynol. The key steps involved in the synthesis are oxa-Michael addition, highly diastereo­selective Brown allylation, and ring closing metathesis (RCM) and cross metathesis (CM) reactions.

Key words

oxa-Michael addition - Brown asymmetric allylation - ring-closing metathesis - cross metathesis

• References

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