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J Pediatr Infect Dis 2016; 11(03): 93-98
DOI: 10.1055/s-0036-1597303
Review Article
Georg Thieme Verlag KG Stuttgart · New York

Infectious Complications of Peritoneal Dialysis in Children with End-Stage Renal Disease

Oana Nicoara
1   Division of Pediatric Nephrology, Medical University of South Carolina, Charleston, South Carolina, United States
,
Michael J. G. Somers
2   Division of Nephrology, Boston Children's Hospital, Boston, Massachusetts, United States
,
Deepa H. Chand
3   Abbvie, Chicago, Illinois, United States
4   Division of Pediatric Nephrology, University of Illinois College of Medicine at Peoria, Peoria, Illinois, United States
› Author Affiliations
Further Information

Publication History

18 July 2016

19 September 2016

Publication Date:
19 December 2016 (online)

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Abstract

End-stage renal disease (ESRD) affects children of all ages worldwide. During their lifetimes, these children undergo a continuous sequence of renal replacement therapies: hemodialysis (HD), peritoneal dialysis (PD), and transplantation, and consequently, face a significantly shortened life expectancy. Although transplant remains the treatment of choice, 75% of children with ESRD now require treatment with dialysis prior to receiving a kidney transplant, and ultimately, upon allograft failure, will need to return to dialysis. Dialysis is, for that reason, a life-saving therapy for children and adolescents with ESRD, and conditions that complicate or negatively impact dialysis need to be prevented or minimized in this population. With patients on PD, peritonitis is an important cause of morbidity, mortality, and functional failure of the peritoneal membrane and a complication that has been reported to occur more commonly in children than in adults.

Keywords

peritoneal dialysis - infections - children
 

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