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J Pediatr Infect Dis 2017; 12(03): 171-175
DOI: 10.1055/s-0037-1602828
DOI: 10.1055/s-0037-1602828
Review Article
Antimicrobial Stewardship for Newborns in the Neonatal Intensive Care Unit
Further Information
Publication History
08 December 2016
26 December 2016
Publication Date:
17 May 2017 (online)
Abstract
Overuse of antibiotics causing antibiotic resistance, an increase in Clostridium difficile infections, and increased adverse drug reactions is a growing problem. To combat this growing threat, the Centers for Disease Control started a program to improve the appropriate use of antimicrobials that focuses on antimicrobial stewardship. In the neonatal intensive care unit (NICU) medically fragile infants are commonly exposed to antibiotics resulting in a growing interest in applying antimicrobial stewardship principles in this patient population. The lack of treatment guidelines and the relatively narrow spectrum of individual antibiotics used to make the NICU a unique environment requiring a specialized approach to antimicrobial stewardship. This article examines the current antibiotic treatment data for common NICU illnesses including early and late-onset sepsis, pneumonia, and necrotizing enterocolitis, then reviews current recommendations for antimicrobial stewardship.
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