CC BY-NC-ND 4.0 · Journal of Child Science 2017; 07(01): e38-e41
DOI: 10.1055/s-0037-1603893
Review Article
Georg Thieme Verlag KG Stuttgart · New York

Follow-up of Newborns, Infants, and Children with Sepsis

P. Dahlem
1   Department of Pediatrics, Medical Centre Coburg, Academic Hospital of the University of Split, Coburg, Germany
P. Biggar
2   Department of Nephrology, Medical Centre Coburg, Academic Hospital of the University of Split, Coburg, Germany
› Author Affiliations
Further Information

Publication History

16 February 2017

22 March 2017

Publication Date:
26 July 2017 (online)


Mortality in newborn infants and children with sepsis is high with survival rates of generally more than 50% in recent studies. Longitudinal follow-up studies have the potential to reveal short-term and lifelong physical, mental, and psychological sequelae. Although no comprehensive follow-up research has yet been performed, a small number of follow-up studies have shown that there is a considerable impact on the patients' lives and their families after hospital discharge. Health-related quality of life also seems to be affected; however, it does not correlate with severity of sepsis or handicap per se. Prematurely born infants, who can develop sequelae directly attributable to prematurity and its consequences, suffer differently from sepsis-related lifelong sequelae compared with older children. Fortunately, time may heal some wounds due to the effect of growth in children. In future, large centers should establish structural follow-up programs for clinical and research purposes to learn more about the needs of affected children and their families.

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