Amer J Perinatol 2018; 35(03): 286-291
DOI: 10.1055/s-0037-1607222
Original Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

The Effect of Delayed Cord Clamping on Moderate and Early Late-Preterm Infants

Arpitha Chiruvolu
Division of Neonatology, Department of Pediatrics, Baylor University Medical Center, Pediatrix Medical Group, Dallas, Texas
Huanying Qin
Department of Quantitative Sciences, Baylor Scott & White Health Care System, Dallas, Texas
Elizabeth T. Nguyen
Department of Medical Education, Texas A & M College of Medicine, Bryan, Texas
Robert W. Inzer
Department of Obstetrics and Gynecology, Baylor University Medical Center, Dallas, Texas
› Author Affiliations
Funding This study received a faculty research grant from the Baylor University Medical Center, Dallas, TX.
Further Information

Publication History

30 April 2017

28 August 2017

Publication Date:
28 September 2017 (eFirst)


Objective This study aims to evaluate the clinical consequences of protocol-driven delayed umbilical cord clamping (DCC) implementation in moderate and early late-preterm (MELP) infants born between 320/7 and 346/7 weeks gestation.

Study Design We conducted a prospective cohort study with a historic control cohort comparison. The prospective study period was 1 year when DCC was performed for 60 seconds duration (DCC cohort, n = 106). The study period for historic control cohort with no DCC was also 1 year before DCC implementation (historic cohort, n = 137).

Results The mean hematocrit at birth was significantly higher in the DCC cohort compared with the historic cohort (49.1 ± 14.9 vs. 45.7 ± 15.7; p = 0.01). Fewer infants in the DCC cohort were admitted to neonatal intensive care unit (NICU) on respiratory support compared with the historic cohort (17.9 vs. 29.9%; p = 0.04). The incidence of respiratory distress syndrome was significantly lower in the DCC cohort compared with the historic cohort (2.8 vs. 14.6%; p = 0.002). There were no differences in the incidence of phototherapy or NICU length of stay (LOS) between groups.

Conclusion In MELP infants, DCC was associated with increased hematocrit and better respiratory transition at birth. DCC was not associated with increased phototherapy or NICU LOS.