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CC BY ND NC 4.0 · SynOpen 2019; 03(02): 59-66
DOI: 10.1055/s-0037-1611876
DOI: 10.1055/s-0037-1611876
paper
First Stereoselective Total Synthesis of Ciryneol C
A.S. thanks UGC, New Delhi, India for the award of a Fellowship. The authors thank CSIR, New Delhi, India for financial support and GAP 0623 Ministry of AYUSH.Weitere Informationen
Publikationsverlauf
Received: 27. März 2019
Accepted after revision: 06. Juni 2019
Publikationsdatum:
25. Juni 2019 (online)
CSIR-IICT, Communication No. IICT/Pubs./2019/064
Abstract
The acetylene derivative Ciryneol C was isolated from the roots of C. japonicum. The asymmetric total synthesis of Ciryneol C was achieved in seven steps, with Horner–Wittig olefination, regioselective epoxide opening, and Cadiot–Chodkiewicz coupling reactions being the key steps.
Key words
acetylene - Cadiot–Chodkiewicz coupling - natural products - Sharpless asymmetric epoxidation - total synthesisSupporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0037-1611876.
- Supporting Information
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