CC BY-NC-ND 4.0 · Arq Bras Neurocir 2012; 31(03): 166-171
DOI: 10.1055/s-0038-1625702
Artigos Originais
Thieme Revinter Publicações Ltda Rio de Janeiro, Brazil

Massive intra and extracranial benign meningioma metastasizing to the lung and spine: the problem of meningiomas classification and iatrogenic metastasizing

Meningioma benigno intra e extracraniano com metástase para pulmão e coluna: o problema da classificação e disseminação iatrogênica
Henning Drews
,
Clemar Correa
,
Hector Navarro Cabrera
,
Eberval Gadelha Figueiredo
,
Leonardo Christiaan Welling
,
Manoel Jacobsen Teixeira
Further Information

Publication History

Publication Date:
11 January 2018 (online)

Abstract

Meningioma is a common CNS tumor and metastasis in these tumours is a rare occurrence. Malignant meningiomas are more prone to metastase. However, there are frequent case reports of metastases in atypical (grade II) and even benign (grade I), which demonstrates the somehow unsatisfying prognostic power of the current classification system. We describe an extraordinary case of a patient with a massive intra and extra-cranial, benign meningioma, metastasizing to both lung and spine. Following the report we discuss 1) some of the problems of classifying meningioma, 2) massive meningiomas and 3) the possibility of intra-operative iatrogenic metastasizing. This case is unique due to its combination of different sites of metastases, massiveness, invasive growth and benign histology. Thus it ranks among those rare but not uncommon complicated courses in meningioma which is otherwise a common benign tumor. Unfortunately the existing classification-criteria do not have sufficient power to predict such complicated courses.

Resumo

Meningioma é um tumor comum que raramente metastatiza, principalmente em casos de meningiomas malignos. Contudo, há casos frequentes de metástases em casos de tumores benignos ou atípicos, o que denota evidente falha no sistema atual de classificação desses tumores. Os autores descrevem o caso de um paciente com extenso meningioma benigno intra e extracraniano que metastizou para pulmões e coluna e adicionalmente discutem questões relativas a classificação e mecanismos de disseminação hematogênica.

1Medical student of Department of Clinical Pharmacology, University Hospital of Tuebingen, Germany.


2Head of Neuro-oncology team Division of Neurosurgery of Hospital das Clínicas, University of Sao Paulo (USP), Brazil.


3Director, Division of Functional Neurosurgery of Hospital das Clínicas, USP, Brazil.


4Head of Neurovascular Group and Supervisor of Division of Neurosurgery of Hospital das Clínicas, USP, Brazil.


5Neurosurgeon, Post-Graduation Program, USP, Brazil.


6Chairman, Division of Neurosurgery Hospital das Clínicas, USP, Brazil.