CC BY 4.0 · Surg J (N Y) 2018; 04(02): e96-e101
DOI: 10.1055/s-0038-1655757
Original Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Patch Angioplasty or Primary Closure Following Carotid Endarterectomy for Symptomatic Carotid Artery Stenosis

Eline Huizing
1   Department of Surgery, Northwest Clinics Alkmaar, Alkmaar, The Netherlands
Cornelis G. Vos
1   Department of Surgery, Northwest Clinics Alkmaar, Alkmaar, The Netherlands
2   Department of Surgery, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands
Robin G. Hulsebos
1   Department of Surgery, Northwest Clinics Alkmaar, Alkmaar, The Netherlands
Peter J. van den Akker
1   Department of Surgery, Northwest Clinics Alkmaar, Alkmaar, The Netherlands
Gert Jan de Borst
3   Department of Surgery, Utrecht University Medical Center, Utrecht, The Netherlands
Çağdaş Ünlü
1   Department of Surgery, Northwest Clinics Alkmaar, Alkmaar, The Netherlands
› Author Affiliations
Further Information

Publication History

04 March 2018

17 April 2018

Publication Date:
15 June 2018 (online)


Objectives Guidelines recommend routine patching to prevent restenosis following carotid endarterectomy, mainly based on studies performed many years ago with different perioperative care and medical treatment compared with current standards. Aim of the present study was to compare primary closure (PRC) versus patch closure (PAC) in a contemporary cohort of patients.

Methods Consecutive patients treated by carotid endarterectomy for symptomatic stenosis between January 2006 and April 2016 were retrospectively analyzed. Primary outcome was restenosis at 6 weeks and 1 year and occurrence of ipsilateral stroke. Secondary outcomes were mortality, complications, and reintervention rates.

Results Five hundred carotid artery endarterectomies were performed. Fifty-nine patients were excluded because eversion endarterectomy was performed or because they were asymptomatic. PRC was performed in 349 and PAC in 92 patients. Restenosis at 6 weeks was 6.0% in the PAC group versus 3.0% in the PRC group (p = 0.200). Restenosis at 1 year was 31.6 versus 14.1%, respectively (p = 0.104). No difference was found for stroke (3.4 vs 1.1%, p = 0.319), death (1.1 vs 0.0%, p = 0.584), or other complications (1.1 vs 0.0%, p = 0.584), respectively.

Conclusions It remains unclear whether routine patching should be recommended for all patients. A strategy of selective patching compared with routine patching, based on internal carotid artery diameter and other patient characteristics, deserves further investigation.

Ethics Approval and Consent

This study was approved by the Noordwest Clinics Alkmaar Ethics Committee and the requirement for informed consent was waived by the committee.

Authors' Contributions

EH data collection, data analysis, writing draft of manuscript.

CV conception and design, data analysis, interpretation, revising manuscript.

RH data interpretation, revising manuscript.

PA data interpretation, revising manuscript.

GB data interpretation, revising manuscript.

CU conception and design, data analysis, interpretation, revising manuscript.

All authors read and approved the final manuscript.

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