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J Pediatr Infect Dis 2018; 13(04): 277-282
DOI: 10.1055/s-0038-1661389
Original Article
Georg Thieme Verlag KG Stuttgart · New York

Antibiotic Susceptibility Profile of ‘Vibrio Cholerae O1 Biotype El Tor Serotype Ogawa’ Outbreak in North Delhi, India

Pragnya Paramita Jena
1   Department of Microbiology, Dr Baba Saheb Ambedkar Medical College and Hospital, GNCT, Delhi, India
,
Renu Gur
1   Department of Microbiology, Dr Baba Saheb Ambedkar Medical College and Hospital, GNCT, Delhi, India
,
Abha Sharma
1   Department of Microbiology, Dr Baba Saheb Ambedkar Medical College and Hospital, GNCT, Delhi, India
,
Shalini Dewan Duggal
1   Department of Microbiology, Dr Baba Saheb Ambedkar Medical College and Hospital, GNCT, Delhi, India
,
Tanisha Bharara
1   Department of Microbiology, Dr Baba Saheb Ambedkar Medical College and Hospital, GNCT, Delhi, India
› Author Affiliations
Further Information

Publication History

19 January 2018

16 May 2018

Publication Date:
08 August 2018 (online)

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Abstract

Background Cholera remains a public health issue, especially in developing countries. We report a cholera outbreak in North Delhi.

Objective To report the causative agent of outbreak and to characterize, biotype, and analyze antimicrobial resistance pattern of V. cholerae isolated from cholera patients admitted to our hospital. The outbreak occurred from July 2016 to August 2016.

Materials and Methods A total of 179 stool samples from pediatrics department were received and processed according to the current Clinical and Laboratory Standards Institute (CLSI) guidelines.

Results Out of 179 stool samples received by the laboratory, 26 samples grew Vibrio cholerae O1 Biotype El Tor. Cefotaxime and ceftriaxone were the most sensitive drugs. All isolates were resistant to cotrimoxazole followed by tetracycline.

Conclusion According to the World Health Organization (WHO), cholera is becoming endemic in Delhi. Emergence of multiple antibiotic-resistant cholera isolates is a concern. Prompt identification and notification of cholera are the key measures to avert cholera outbreak. Clean water supply and improved sanitation measures should be taken for prevention of cholera.

Keywords

cholera - antibiotic resistance - public health - outbreak - North Delhi
 

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