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Am J Perinatol 2019; 36(09): 918-923
DOI: 10.1055/s-0038-1675620
Original Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Longitudinal Measurements of Resting Energy Expenditure by Indirect Calorimetry in Healthy Term Infants during the First 2 Months of Life

Sourabh Verma
1   Division of Neonatology, Department of Pediatrics, NYU School of Medicine, New York, New York
,
Sean M. Bailey
1   Division of Neonatology, Department of Pediatrics, NYU School of Medicine, New York, New York
,
Pradeep V. Mally
1   Division of Neonatology, Department of Pediatrics, NYU School of Medicine, New York, New York
,
Heather B. Howell
1   Division of Neonatology, Department of Pediatrics, NYU School of Medicine, New York, New York
› Author Affiliations Funding The Stefan Bennett Fellowship Research Fund in Neonatology and KiDS of NYU provided funding for this study.
Further Information

Publication History

30 July 2018

20 September 2018

Publication Date:
10 November 2018 (online)

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Abstract

Objective To determine longitudinal measurements of resting energy expenditure (REE) by indirect calorimetry (IC) in healthy term infants during the first 2 months of life.

Study Design An outpatient prospective pilot study was performed in healthy term infants to estimate REE by measuring expired gas fractions of oxygen (O2) and carbon dioxide (CO2) with IC in a respiratory and metabolic steady state.

Results A total of 30 measurements were performed. Fourteen subjects completed measurements at both 1 and 2 months of life, and two subjects had only measurements made at 1 month of life. Mean REE values were 64.1 ± 12.7 and 58.4 ± 14.3 kcal/kg/d at 1 and 2 months of age, respectively. Mean O2 consumption and CO2 production measurements were 9.3 ± 2.0 and 7.7 ± 1.2 mL/kg/min and 8.1 ± 2.2 and 6.4 ± 1.1 mL/kg/min at 1 and 2 months of age, respectively.

Conclusion This pilot study demonstrates longitudinal measurements of REE by IC in healthy term infants during the first 2 months of life. We also demonstrate that, overall, there is consistency in REE values in this population, with a likely decrease in individual longitudinal measurements over the first 2 months of life.

Keywords

resting energy expenditure - indirect calorimetry - healthy term infants - nutrition
 

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