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Am J Perinatol 2020; 37(04): 436-452
DOI: 10.1055/s-0039-1681095
Original Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Developing a Core Outcome Set for Cesarean Delivery Maternal Infectious Morbidity Outcomes

Kristin E. Briscoe
1   Department of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis, Indiana
,
David M. Haas
1   Department of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis, Indiana
› Author Affiliations
Further Information

Publication History

11 December 2018

25 January 2019

Publication Date:
28 February 2019 (online)

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Abstract

Objective This study aimed to develop a core outcome set of primary outcomes for studies involving cesarean deliveries with infectious morbidity outcomes.

Study Design Authors reported primary outcomes from 11 Cochrane systematic reviews (SRs), 12 other SRs, and 327 randomized controlled trials (RCTs). These outcomes were condensed into 20 primary outcome groups. Next, a modified Delphi technique was used to gain consensus on key outcomes. Authors from included SRs were sent a questionnaire consisting of a free response and multiple-choice questions. These data were used to propose a set of core outcomes.

Results The most frequent outcomes in RCTs were composite “infectious outcomes” (24%) with the second most common being endometritis (12%). The most common reported SR outcomes were wound infection (21%) and endometritis (16%). For the Delphi survey free response portion, wound infection (88%) and endometritis (79%) were the most commonly endorsed outcomes. Chosen list outcomes were maternal mortality (83%), wound infection (83%), wound complications (86%), and postpartum endometritis (80%). The proposed final core outcome set for cesarean trials was endometritis (primary outcome), maternal mortality, wound infection, wound complications, febrile morbidity, and neonatal morbidity.

Conclusion Utilizing defined core outcomes in all studies of cesarean section can harmonize trial reports and allow data synthesis for meta-analyses.

Keywords

cesarean delivery - pregnancy - infection - systematic review - core outcomes

Authors' Contribution

Both authors conceived of the project, wrote the protocol, identified and abstracted information from studies, conceived of and implemented the various surveys, analyzed data, and prepared the final manuscript.


Note

Part of this work was presented as an oral presentation at the 2016 Central Association of Obstetricians and Gynecologists Annual Meeting in Las Vegas, NV.


Ethical Approval

This study was approved by the governing Indiana University-IUPUI IRB, protocol #1509104479 (Approved 9/23/2015).


Supplementary Material

 

  • References

  • 1 Martin JA, Hamilton BE, Osterman MJ, Curtin SC, Matthews TJ. Births: final data for 2012. Nat Vital Stat Rep 2013; 62 (09) 1-68
    PubMedGoogle Scholar
  • 2 Molina G, Weiser TG, Lipsitz SR. , et al. Relationship between cesarean delivery rate and maternal and neonatal mortality. JAMA 2015; 314 (21) 2263-2270
    CrossrefPubMedGoogle Scholar
  • 3 Yokoe DS, Christiansen CL, Johnson R. , et al. Epidemiology of and surveillance for postpartum infections. Emerg Infect Dis 2001; 7 (05) 837-841
    CrossrefPubMedGoogle Scholar
  • 4 Anderson ER, Gates S. Techniques and materials for closure of the abdominal wall in caesarean section. Cochrane Database Syst Rev 2004; (04) CD004663
    PubMedGoogle Scholar
  • 5 Bamigboye AA, Hofmeyr GJ. Closure versus non-closure of the peritoneum at caesarean section: short- and long-term outcomes. Cochrane Database Syst Rev 2014; (08) CD000163
    PubMedGoogle Scholar
  • 6 Dodd JM, Anderson ER, Gates S. Surgical techniques for uterine incision and uterine closure at the time of caesarean section. Cochrane Database Syst Rev 2008; (03) CD004732
    PubMedGoogle Scholar
  • 7 Gates S, Anderson ER. Wound drainage for caesarean section. Cochrane Database Syst Rev 2013; (12) CD004549
    PubMedGoogle Scholar
  • 8 Gyte GM, Dou L, Vazquez JC. Different classes of antibiotics given to women routinely for preventing infection at caesarean section. Cochrane Database Syst Rev 2014; (11) CD008726
    PubMedGoogle Scholar
  • 9 Haas DM, Morgan S, Contreras K. Vaginal preparation with antiseptic solution before cesarean section for preventing postoperative infections. Cochrane Database Syst Rev 2014; (12) CD007892
    PubMedGoogle Scholar
  • 10 Liabsuetrakul T, Peeyananjarassri K. Mechanical dilatation of the cervix at non-labour caesarean section for reducing postoperative morbidity. Cochrane Database Syst Rev 2011; (11) CD008019
    PubMedGoogle Scholar
  • 11 Mackeen AD, Berghella V, Larsen M-L. Techniques and materials for skin closure in caesarean section. Cochrane Database Syst Rev 2012; (09) CD003577
    PubMedGoogle Scholar
  • 12 Mackeen AD, Packard RE, Ota E, Berghella V, Baxter JK. Timing of intravenous prophylactic antibiotics for preventing postpartum infectious morbidity in women undergoing cesarean delivery. Cochrane Database Syst Rev 2014; (12) CD009516
    PubMedGoogle Scholar
  • 13 Mathai M, Hofmeyr GJ, Mathai NE. Abdominal surgical incisions for caesarean section. Cochrane Database Syst Rev 2013; (05) CD004453
    PubMedGoogle Scholar
  • 14 Smaill FM, Grivell RM. Antibiotic prophylaxis versus no prophylaxis for preventing infection after cesarean section. Cochrane Database Syst Rev 2014; (10) CD007482
    PubMedGoogle Scholar
  • 15 Sinha IP, Smyth RL, Williamson PR. Using the Delphi technique to determine which outcomes to measure in clinical trials: recommendations for the future based on a systematic review of existing studies. PLoS Med 2011; 8 (01) e1000393
    CrossrefPubMedGoogle Scholar
  • 16 Anderson V, Chaboyer W, Gillespie B. The relationship between obesity and surgical site infections in women undergoing caesarean sections: an integrative review. Midwifery 2013; 29 (12) 1331-1338
    CrossrefPubMedGoogle Scholar
  • 17 Baaqeel H, Baaqeel R. Timing of administration of prophylactic antibiotics for caesarean section: a systematic review and meta-analysis. BJOG 2013; 120 (06) 661-669
    CrossrefPubMedGoogle Scholar
  • 18 Bamigboye AA, Hofmeyr GJ. Non-closure of peritoneal surfaces at caesarean section--a systematic review. S Afr Med J 2005; 95 (02) 123-126
    PubMedGoogle Scholar
  • 19 Chelmow D, Rodriguez EJ, Sabatini MM. Suture closure of subcutaneous fat and wound disruption after cesarean delivery: a meta-analysis. Obstet Gynecol 2004; 103 (5, Pt 1): 974-980
    CrossrefPubMedGoogle Scholar
  • 20 Chelmow D, Ruehli MS, Huang E. Prophylactic use of antibiotics for nonlaboring patients undergoing cesarean delivery with intact membranes: a meta-analysis. Am J Obstet Gynecol 2001; 184 (04) 656-661
    CrossrefPubMedGoogle Scholar
  • 21 Clay FS, Walsh CA, Walsh SR. Staples vs subcuticular sutures for skin closure at cesarean delivery: a metaanalysis of randomized controlled trials. Am J Obstet Gynecol 2011; 204 (05) 378-383
    CrossrefPubMedGoogle Scholar
  • 22 Costantine MM, Rahman M, Ghulmiyah L. , et al. Timing of perioperative antibiotics for cesarean delivery: a metaanalysis. Am J Obstet Gynecol 2008; 199 (03) 301.e1-301.e6
    CrossrefPubMedGoogle Scholar
  • 23 Hellums EK, Lin MG, Ramsey PS. Prophylactic subcutaneous drainage for prevention of wound complications after cesarean delivery--a metaanalysis. Am J Obstet Gynecol 2007; 197 (03) 229-235
    CrossrefPubMedGoogle Scholar
  • 24 Klingel ML, Patel SV. A meta-analysis of the effect of inspired oxygen concentration on the incidence of surgical site infection following cesarean section. Int J Obstet Anesth 2013; 22 (02) 104-112
    CrossrefPubMedGoogle Scholar
  • 25 Roberge S, Demers S, Berghella V, Chaillet N, Moore L, Bujold E. Impact of single- vs double-layer closure on adverse outcomes and uterine scar defect: a systematic review and metaanalysis. Am J Obstet Gynecol 2014; 211 (05) 453-460
    CrossrefPubMedGoogle Scholar
  • 26 Sun J, Ding M, Liu J. , et al. Prophylactic administration of cefazolin prior to skin incision versus antibiotics at cord clamping in preventing postcesarean infectious morbidity: a systematic review and meta-analysis of randomized controlled trials. Gynecol Obstet Invest 2013; 75 (03) 175-178
    CrossrefPubMedGoogle Scholar
  • 27 Tita AT, Rouse DJ, Blackwell S, Saade GR, Spong CY, Andrews WW. Emerging concepts in antibiotic prophylaxis for cesarean delivery: a systematic review. Obstet Gynecol 2009; 113 (03) 675-682
    CrossrefPubMedGoogle Scholar
  • 28 CAESAR study collaborative group. Caesarean section surgical techniques: a randomised factorial trial (CAESAR). BJOG 2010; 117 (11) 1366-1376
    CrossrefPubMedGoogle Scholar
  • 29 Guyot-Cottrel A. Essai CHORUS: Comparaison de l'aspect échographique de la cicatrice de césarienne selon une fermeture utérine en un plan ou en deux plans. Paris: Université Paris Descarte; 2011
    Google Scholar
  • 30 Aabakke AJ, Hare KJ, Krebs L, Secher NJ. Sharp compared with blunt fascial incision at cesarean delivery: a randomized controlled trial with each case as her own control. Eur J Obstet Gynecol Reprod Biol 2014; 172: 40-45
    CrossrefPubMedGoogle Scholar
  • 31 Abalos E, Addo V, Brocklehurst P. , et al; CORONIS Collaborative Group. Caesarean section surgical techniques (CORONIS): a fractional, factorial, unmasked, randomised controlled trial. Lancet 2013; 382 (9888): 234-248
    CrossrefPubMedGoogle Scholar
  • 32 Adam I, Adam ES, Gerais AS. Randomized trial of ceftriaxone prophylaxis in elective cesarean section. Saudi Med J 2005; 26 (03) 500-501
    PubMedGoogle Scholar
  • 33 Adeleye JA, Osinusi BO. The use of prophylactic antibiotics in caesarean sections. Singapore J Obstet Gynecol 1981; 12: 29-34
    PubMedGoogle Scholar
  • 34 Admadé B, Reyes O. Supplemental perioperative oxygen (80% FIO2) for the prevention of surgical site infection after emergency cesarean section. ISRN Infect Dis 2013; 2013: 526163
    PubMedGoogle Scholar
  • 35 Ahmed B, Abu Nahia F, Abushama M. Routine cervical dilatation during elective cesarean section and its influence on maternal morbidity: a randomized controlled study. J Perinat Med 2005; 33 (06) 510-513
    PubMedGoogle Scholar
  • 36 Ahmed ET, Mirghani OA, Gerais AS, Adam I. Ceftriaxone versus ampicillin/cloxacillin as antibiotic prophylaxis in elective caesarean section. East Mediterr Health J 2004; 10 (03) 277-288
    PubMedGoogle Scholar
  • 37 Ahmed SR, Ellah MA, Mohamed OA, Eid HM. Prepregnancy obesity and pregnancy outcome. Int J Health Sci (Qassim) 2009; 3 (02) 203-208
    PubMedGoogle Scholar
  • 38 Kumar SA. Nonclosure of parietal and visceral peritoneum during cesarean section. J Obstet Gynaecol India 2003; 53 (02) 153-157
    PubMedGoogle Scholar
  • 39 Kumar SA. Single versus double layer closure of low transverse uterine incision and caesarean section. J Obstet Gynaecol India 2005; 55: 231-236
    PubMedGoogle Scholar
  • 40 Alanis MC, Villers MS, Law TL, Steadman EM, Robinson CJ. Complications of cesarean delivery in the massively obese parturient. Am J Obstet Gynecol 2010; 203 (03) 271.e1-271.e7
    CrossrefPubMedGoogle Scholar
  • 41 Alekwe LO, Kuti O, Orji EO, Ogunniyi SO. Comparison of ceftriaxone versus triple drug regimen in the prevention of cesarean section infectious morbidities. J Matern Fetal Neonatal Med 2008; 21 (09) 638-642
    CrossrefPubMedGoogle Scholar
  • 42 Al-Inany H, Youssef G, Abd ElMaguid A, Abdel Hamid M, Naguib A. Value of subcutaneous drainage system in obese females undergoing cesarean section using pfannenstiel incision. Gynecol Obstet Invest 2002; 53 (02) 75-78
    CrossrefPubMedGoogle Scholar
  • 43 Allaire AD, Fisch J, McMahon MJ. Subcutaneous drain vs. suture in obese women undergoing cesarean delivery. A prospective, randomized trial. J Reprod Med 2000; 45 (04) 327-331
    PubMedGoogle Scholar
  • 44 Allen JL, Rampone JF, Wheeless CR. Use of a prophylactic antibiotic in elective major gynecologic operations. Obstet Gynecol 1972; 39 (02) 218-224
    PubMedGoogle Scholar
  • 45 Altinbas SK, Cenksoy P, Tapisiz OL. , et al. Parietal peritoneal closure versus non-closure at caesarean section: which technique is feasible to perform?. J Matern Fetal Neonatal Med 2013; 26 (11) 1128-1131
    CrossrefPubMedGoogle Scholar
  • 46 Andrews WW, Hauth JC, Cliver SP, Savage K, Goldenberg RL. Randomized clinical trial of extended spectrum antibiotic prophylaxis with coverage for Ureaplasma urealyticum to reduce post-cesarean delivery endometritis. Obstet Gynecol 2003; 101 (06) 1183-1189
    PubMedGoogle Scholar
  • 47 Ansaloni L, Brundisini R, Morino G, Kiura A. Prospective, randomized, comparative study of Misgav Ladach versus traditional cesarean section at Nazareth Hospital, Kenya. World J Surg 2001; 25 (09) 1164-1172
    CrossrefPubMedGoogle Scholar
  • 48 Anteby EY, Kruchkovich J, Kapustian V, Gdalevich M, Shenhav S, Gemer O. Short-term effects of closure versus non-closure of the visceral and parietal peritoneum at cesarean section: a prospective randomized study. J Obstet Gynaecol Res 2009; 35 (06) 1026-1030
    CrossrefPubMedGoogle Scholar
  • 49 Apuzzio JJ, Ganesh VV, Pelosi MA, Frisoli G. The effect of prophylactic antibiotics on risk factors for endomyometritis in adolescent patients undergoing cesarean section. J Adolesc Health Care 1984; 5 (03) 163-166
    CrossrefPubMedGoogle Scholar
  • 50 Asghania M, Mirblouk F, Shakiba M, Faraji R. Preoperative vaginal preparation with povidone-iodine on post-caesarean infectious morbidity. J Obstet Gynaecol 2011; 31 (05) 400-403
    CrossrefPubMedGoogle Scholar
  • 51 Bagratee JS, Moodley J, Kleinschmidt I, Zawilski W. A randomised controlled trial of antibiotic prophylaxis in elective caesarean delivery. BJOG 2001; 108 (02) 143-148
    PubMedGoogle Scholar
  • 52 Baksu A, Kalan A, Ozkan A, Baksu B, Tekelioğlu M, Goker N. The effect of placental removal method and site of uterine repair on postcesarean endometritis and operative blood loss. Acta Obstet Gynecol Scand 2005; 84 (03) 266-269
    CrossrefPubMedGoogle Scholar
  • 53 Banad HP. Single versus Double Layer Uterine Closure in Lower Segment Cesarean Section. A Comparative Study [dissertation]. Gijapur, India: Rajv Gandhi University of Health Sciences; 2006
    Google Scholar
  • 54 Basha SL, Rochon ML, Quiñones JN, Coassolo KM, Rust OA, Smulian JC. Randomized controlled trial of wound complication rates of subcuticular suture vs staples for skin closure at cesarean delivery. Am J Obstet Gynecol 2010; 203 (03) 285.e1-285.e8
    CrossrefPubMedGoogle Scholar
  • 55 Bastani P, Pourabolghasem S, Abbasalizadeh F, Motvalli L. Comparison of neonatal and maternal outcomes associated with head-pushing and head-pulling methods for impacted fetal head extraction during cesarean delivery. Int J Gynaecol Obstet 2012; 118 (01) 1-3
    CrossrefPubMedGoogle Scholar
  • 56 Battarino O, Battarino A. Short-term antibiotic prophylaxis in cesarean section [in Italian]. Minerva Ginecol 1988; 40 (09) 563-567
    PubMedGoogle Scholar
  • 57 Benigno BB, Ford LC, Lawrence WD, Ledger WJ, Ling FW, McNeeley SG. A double-blind, controlled comparison of piperacillin and cefoxitin in the prevention of postoperative infection in patients undergoing cesarean section. Surg Gynecol Obstet 1986; 162 (01) 1-7
    PubMedGoogle Scholar
  • 58 Berthet J, Peresse JF, Rosier P, Racinet C. Comparative study of Pfannenstiel's incision and transverse abdominal incision in gynecologic and obstetric surgery [in French]. Presse Med 1989; 18 (29) 1431-1433
    PubMedGoogle Scholar
  • 59 Bhattacharjee N, Saha SP, Patra KK, Mitra U, Ghoshroy SC. Optimal timing of prophylactic antibiotic for cesarean delivery: a randomized comparative study. J Obstet Gynaecol Res 2013; 39 (12) 1560-1568
    CrossrefPubMedGoogle Scholar
  • 60 Bibi M, Megdiche H, Ghanem H. , et al. Antibiotic prophylaxis in a priori cesarean sections without a high risk of infection. Experiences of a Tunisian maternity department [in French]. J Gynecol Obstet Biol Reprod (Paris) 1994; 23 (04) 451-455
    PubMedGoogle Scholar
  • 61 Bilgin T, Ozan H, Dirgen A, Esmer A. Comparison of four different antibiotics as prophylaxis in caesarean section. J Obstet Gynaecol 1998; 18 (06) 546-547
    CrossrefPubMedGoogle Scholar
  • 62 Björklund K, Kimaro M, Urassa E, Lindmark G. Introduction of the Misgav Ladach caesarean section at an African tertiary centre: a randomised controlled trial. BJOG 2000; 107 (02) 209-216
    CrossrefPubMedGoogle Scholar
  • 63 Borowski K, Andrews J, Hocking M, Hansen W, Fleener D, Syrop C. 183: Ultrasonographic detection of cesarean scar defects in a trial of single versus double layer closure. Am J Obstet Gynecol 2007; 197 (06) S62
    PubMedGoogle Scholar
  • 64 Bourgeois FJ, Pinkerton JA, Andersen W, Thiagarajah S. Antibiotic irrigation prophylaxis in the high-risk cesarean section patient. Am J Obstet Gynecol 1985; 153 (02) 197-201
    CrossrefPubMedGoogle Scholar
  • 65 Bracero LA. Ampicillin/sulbactam versus cefotetan for the prevention of infection following cesarean delivery in high-risk patients: a randomized double-blind trial. Gynecol Obstet Invest 1997; 44 (01) 21-25
    CrossrefPubMedGoogle Scholar
  • 66 Busowski J, Porter KB, Pendergraft S, O'Brien WF, Vodra J. Antibiotic prophylaxis for cesarean delivery: a randomized trial of cefotetan, ampicillin-sulbactam and ciprofloxacin. Prenat Neonatal Med 2000; 5 (06) 357-362
    PubMedGoogle Scholar
  • 67 Carl SH, Hampton R. Normal saline pelvic and intrauterine irrigation in the high-risk cesarean section (CS) patient as a safe and cost-effective method of infection prophylaxis. Am J Obstet Gynecol 2000; 182 (1, Pt2): S96
    PubMedGoogle Scholar
  • 68 Carlson C, Duff P. Antibiotic prophylaxis for cesarean delivery: is an extended-spectrum agent necessary?. Obstet Gynecol 1990; 76 (3, Pt 1): 343-346
    PubMedGoogle Scholar
  • 69 Ceci O, Cantatore C, Scioscia M. , et al. Ultrasonographic and hysteroscopic outcomes of uterine scar healing after cesarean section: comparison of two types of single-layer suture. J Obstet Gynaecol Res 2012; 38 (11) 1302-1307
    CrossrefPubMedGoogle Scholar
  • 70 Cetin A, Cetin M. Superficial wound disruption after cesarean delivery: effect of the depth and closure of subcutaneous tissue. Int J Gynaecol Obstet 1997; 57 (01) 17-21
    CrossrefPubMedGoogle Scholar
  • 71 Chan AC, Leung AK, Chin RK, Chang AM. Single dose prophylactic antibiotics in caesarean sections. Aust N Z J Obstet Gynaecol 1989; 29 (02) 107-109
    CrossrefPubMedGoogle Scholar
  • 72 Chandra P, Schiavello HJ, Kluge JE, Holloway SL. Manual removal of the placenta and postcesarean endometritis. J Reprod Med 2002; 47 (02) 101-106
    PubMedGoogle Scholar
  • 73 Chanrachakul B, Hamontri S, Herabutya Y. A randomized comparison of postcesarean pain between closure and nonclosure of peritoneum. Eur J Obstet Gynecol Reprod Biol 2002; 101 (01) 31-35
    CrossrefPubMedGoogle Scholar
  • 74 Chantharojwong P. An efficacy study of ampicillin versus cefazolin prophylaxis in patients undergoing cesarean section. J Med Assoc Thai 1993; 76 (03) 165-170
    PubMedGoogle Scholar
  • 75 Chapman SJ, Owen J, Hauth JC. One- versus two-layer closure of a low transverse cesarean: the next pregnancy. Obstet Gynecol 1997; 89 (01) 16-18
    CrossrefPubMedGoogle Scholar
  • 76 Chelmow D, Huang E, Strohbehn K. Closure of the subcutaneous dead space and wound disruption after Cesarean delivery. J Matern Fetal Neonatal Med 2002; 11 (06) 403-408
    CrossrefPubMedGoogle Scholar
  • 77 Chitra KLS, Nirmala AP, Radhakrishna G, Jayanthi NV, Shanthi JS. Misgav Ladach cesarean section vs Pfannenstiel cesarean section. J Obstet Gynaecol India 2004; 54: 473-477
    PubMedGoogle Scholar
  • 78 Conover WB, Moore TR. Comparison of irrigation and intravenous antibiotic prophylaxis at cesarean section. Obstet Gynecol 1984; 63 (06) 787-791
    PubMedGoogle Scholar
  • 79 Cordtz T, Schouenborg L, Laursen K. , et al. The effect of incisional plastic drapes and redisinfection of operation site on wound infection following caesarean section. J Hosp Infect 1989; 13 (03) 267-272
    CrossrefPubMedGoogle Scholar
  • 80 Cormier P, Leng JJ, Janky E, Duthil B, Brouste V. Prevention of infectious complications after cesarean section by the use of cefotetan [in French]. J Gynecol Obstet Biol Reprod (Paris) 1989; 18 (03) 388-392
    PubMedGoogle Scholar
  • 81 Cormier P, Leng JJ, Janky E, Duthil B, Brouste V. Prevention of infectious complications after cesarean section by the use of cefotetan [in French]. J Gynecol Obstet Biol Reprod (Paris) 1989; 18 (03) 388-392
    PubMedGoogle Scholar
  • 82 Coutinho IC, Ramos de Amorim MM, Katz L, Bandeira de Ferraz AA. Uterine exteriorization compared with in situ repair at cesarean delivery: a randomized controlled trial. Obstet Gynecol 2008; 111 (03) 639-647
    CrossrefPubMedGoogle Scholar
  • 83 Crombleholme WR, Green JR, Ohm-Smith M. , et al. Cesarean section prophylaxis: comparison of two doses with three doses of mezlocillin. Am J Reprod Immunol Microbiol 1987; 13 (03) 71-75
    CrossrefPubMedGoogle Scholar
  • 84 Crombleholme WR, Green JR, Ohm-Smith M. , et al. Prophylaxis in caesarean section with cefmetazole and cefoxitin. J Antimicrob Chemother 1989; 23 (Suppl D): 97-104
    CrossrefPubMedGoogle Scholar
  • 85 Cromi A, Ghezzi F, Di Naro E, Siesto G, Loverro G, Bolis P. Blunt expansion of the low transverse uterine incision at cesarean delivery: a randomized comparison of 2 techniques. Am J Obstet Gynecol 2008; 199 (03) 292.e1-292.e6
    CrossrefPubMedGoogle Scholar
  • 86 Cromi A, Ghezzi F, Gottardi A, Cherubino M, Uccella S, Valdatta L. Cosmetic outcomes of various skin closure methods following cesarean delivery: a randomized trial. Am J Obstet Gynecol 2010; 203 (01) 36.e1-36.e8
    CrossrefPubMedGoogle Scholar
  • 87 Cunningham FG, Hauth JC, Strong JD, Kappus SS. Infectious morbidity following cesarean section. Comparison of two treatment regimens. Obstet Gynecol 1978; 52 (06) 656-661
    PubMedGoogle Scholar
  • 88 Cunningham FG, Leveno KJ, DePalma RT, Roark M, Rosenfeld CR. Perioperative antimicrobials for cesarean delivery: before or after cord clamping?. Obstet Gynecol 1983; 62 (02) 151-154
    PubMedGoogle Scholar
  • 89 D'Angelo LJ, Sokol RJ. Short- versus long-course prophylactic antibiotic treatment in Cesarean section patients. Obstet Gynecol 1980; 55 (05) 583-586
    PubMedGoogle Scholar
  • 90 Dani C, Reali MF, Oliveto R, Temporin GF, Bertini G, Rubaltelli FF. Short-term outcome of newborn infants born by a modified procedure of cesarean section. A prospective randomized study. Acta Obstet Gynecol Scand 1998; 77 (09) 929-931
    CrossrefPubMedGoogle Scholar
  • 91 Darj E, Nordström ML. The Misgav Ladach method for cesarean section compared to the Pfannenstiel method. Acta Obstet Gynecol Scand 1999; 78 (01) 37-41
    CrossrefPubMedGoogle Scholar
  • 92 Dashow EE, Read JA, Coleman FH. Randomized comparison of five irrigation solutions at cesarean section. Obstet Gynecol 1986; 68 (04) 473-478
    PubMedGoogle Scholar
  • 93 de Boer CN, Thornton JG. Prophylactic short course rectal metronidazole for cesarean section. A double-blind controlled trial of a simple low cost regimen. Int J Gynaecol Obstet 1989; 28 (02) 103-107
    CrossrefPubMedGoogle Scholar
  • 94 de Graaf IM, Oude Rengerink K, Wiersma IC, Donker ME, Mol BW, Pajkrt E. Techniques for wound closure at caesarean section: a randomized clinical trial. Eur J Obstet Gynecol Reprod Biol 2012; 165 (01) 47-52
    CrossrefPubMedGoogle Scholar
  • 95 Del Valle GO, Combs P, Qualls C, Curet LB. Does closure of Camper fascia reduce the incidence of post-cesarean superficial wound disruption?. Obstet Gynecol 1992; 80 (06) 1013-1016
    PubMedGoogle Scholar
  • 96 De-Lalla FOG, Fratoni A, Papadia LS, Mancuso S. Single-dose mezlocillin versus single-dose cefotetan for prophylaxis in cesarean section. Paper presented at: 12th World Congress of Gynecology and Obstetrics; October 23–28, 1988; Rio de Janeiro, Brazil
    PubMedGoogle Scholar
  • 97 DePalma RT, Cunningham FG, Leveno KJ, Roark ML. Continuing investigation of women at high risk for infection following cesarean delivery. Three-dose perioperative antimicrobial therapy. Obstet Gynecol 1982; 60 (01) 53-59
    PubMedGoogle Scholar
  • 98 Dillon WP, Seigel MS, Lele AS, O'Leary JA. Evaluation of cefoxitin prophylaxis for cesarean section. Int J Gynaecol Obstet 1981; 19 (02) 133-139
    CrossrefPubMedGoogle Scholar
  • 99 Doğanay M, Tonguc EA, Var T. Effects of method of uterine repair on surgical outcome of cesarean delivery. Int J Gynaecol Obstet 2010; 111 (02) 175-178
    CrossrefPubMedGoogle Scholar
  • 100 Donnenfeld AE, Otis C, Weiner S. Antibiotic prophylaxis in cesarean section. Comparison of intrauterine lavage and intravenous administration. J Reprod Med 1986; 31 (01) 15-18
    PubMedGoogle Scholar
  • 101 Duff P, Park RC. Antibiotic prophylaxis for cesarean section in a military population. Mil Med 1980; 145 (06) 377-381
    CrossrefPubMedGoogle Scholar
  • 102 Duff P, Robertson AW, Read JA. Single-dose cefazolin versus cefonicid for antibiotic prophylaxis in cesarean delivery. Obstet Gynecol 1987; 70 (05) 718-721
    PubMedGoogle Scholar
  • 103 Duff P, Smith PN, Keiser JF. Antibiotic prophylaxis in low-risk cesarean section. J Reprod Med 1982; 27 (03) 133-138
    PubMedGoogle Scholar
  • 104 Duggal N, Poddatoori V, Noroozkhani S, Siddik-Ahmad RI, Caughey AB. Perioperative oxygen supplementation and surgical site infection after cesarean delivery: a randomized trial. Obstet Gynecol 2013; 122 (01) 79-84
    CrossrefPubMedGoogle Scholar
  • 105 El-Gharib MN, Awara AM. Ultrasound evaluation of the uterine scar thickness after single versus double layer closure of transverse lower segment cesarean section. J Basic Clin Reprod Sci 2013; 2: 42-45
    CrossrefPubMedGoogle Scholar
  • 106 Elliott JP, Flaherty JF. Comparison of lavage or intravenous antibiotics at cesarean section. Obstet Gynecol 1986; 67 (01) 29-32
    PubMedGoogle Scholar
  • 107 Engel K, Amir-Moazami B, Karschnia R, Hahn T. Advantages and hazards of preventing infection following cesarean section--clinical and bacteriologic results of a high-dosage treatment with mezlocillin and oxacillin short-term preventive following clamping of the umbilical cord [in German]. Geburtshilfe Frauenheilkd 1984; 44 (03) 162-170
    Article in Thieme ConnectPubMedGoogle Scholar
  • 108 Escobedo Lobatón JM, Rodríguez Hinojosa DE, Kistner Garza AM, Benavides de Anda L. Prophylactic use of antibiotics in cesarean section [in Spanish]. Ginecol Obstet Mex 1991; 59 (01) 35-38
    PubMedGoogle Scholar
  • 109 Ezechi OC, Edet A, Akinlade H, Gab-Okafor CV, Herbertson E. Incidence and risk factors for caesarean wound infection in Lagos Nigeria. BMC Res Notes 2009; 2: 186
    CrossrefPubMedGoogle Scholar
  • 110 Faro S, Martens MG, Hammill HA, Riddle G, Tortolero G. Antibiotic prophylaxis: is there a difference?. Am J Obstet Gynecol 1990; 162 (04) 900-907
    CrossrefPubMedGoogle Scholar
  • 111 Fejgin MD, Markov S, Goshen S, Segal J, Arbel Y, Lang R. Antibiotic for cesarean section: the case for ‘true’ prophylaxis. Int J Gynaecol Obstet 1993; 43 (03) 257-261
    CrossrefPubMedGoogle Scholar
  • 112 Ferrari AG, Frigerio LG, Candotti G. , et al. Can Joel-Cohen incision and single layer reconstruction reduce cesarean section morbidity?. Int J Gynaecol Obstet 2001; 72 (02) 135-143
    CrossrefPubMedGoogle Scholar
  • 113 Figueroa D, Jauk VC, Szychowski JM. , et al. Surgical staples compared with subcuticular suture for skin closure after cesarean delivery: a randomized controlled trial. Obstet Gynecol 2013; 121 (01) 33-38
    CrossrefPubMedGoogle Scholar
  • 114 Ford LC. Cost of antibiotic prophylaxis in cesarean section. Drug Intell Clin Pharm 1986; 20 (7–8): 592-593
    PubMedGoogle Scholar
  • 115 Franchi M, Ghezzi F, Balestreri D. , et al. A randomized clinical trial of two surgical techniques for cesarean section. Am J Perinatol 1998; 15 (10) 589-594
    Article in Thieme ConnectPubMedGoogle Scholar
  • 116 Franchi M, Ghezzi F, Raio L. , et al. Joel-Cohen or Pfannenstiel incision at cesarean delivery: does it make a difference?. Acta Obstet Gynecol Scand 2002; 81 (11) 1040-1046
    CrossrefPubMedGoogle Scholar
  • 117 Francis C, Mumford M, Strand ML, Moore ES, Strand EA. Timing of prophylactic antibiotic at cesarean section: a double-blinded, randomized trial. J Perinatol 2013; 33 (10) 759-762
    CrossrefPubMedGoogle Scholar
  • 118 Freeman GM. The efficacy of prophylactic antibiotics in high-risk patients undergoing cesarean section. J Am Osteopath Assoc 1982; 81 (09) 610-615
    PubMedGoogle Scholar
  • 119 Frishman GN, Schwartz T, Hogan JW. Closure of Pfannenstiel skin incisions. Staples vs. subcuticular suture. J Reprod Med 1997; 42 (10) 627-630
    PubMedGoogle Scholar
  • 120 Fugère P, Turgeon P, Boucher M, Verschelden G, Lemay M. Use of cephalosporins as antibiotic prophylaxis in cesarean section [in French]. Can Med Assoc J 1983; 129 (02) 132-135
    PubMedGoogle Scholar
  • 121 Gaertner I, Burkhardt T, Beinder E. Scar appearance of different skin and subcutaneous tissue closure techniques in caesarean section: a randomized study. Eur J Obstet Gynecol Reprod Biol 2008; 138 (01) 29-33
    CrossrefPubMedGoogle Scholar
  • 122 Galaal KA, Krolikowski A. A randomized controlled study of peritoneal closure at cesarean section. Saudi Med J 2000; 21 (08) 759-761
    PubMedGoogle Scholar
  • 123 Galask RP, Benigno BB, Cunningham FG. , et al. Results of a multicenter comparative study of single-dose cefotetan and multiple-dose cefoxitin as prophylaxis in patients undergoing cesarean section. Am J Surg 1988; 155 (5A): 86-90
    CrossrefPubMedGoogle Scholar
  • 124 Gall SA. The efficacy of prophylactic antibiotics in cesarean section. Am J Obstet Gynecol 1979; 134 (05) 506-511
    CrossrefPubMedGoogle Scholar
  • 125 Ganesh V, Apuzzio JJ, Dispenziere B, Patel K, Bergen B, Louria DB. Single-dose trimethoprim-sulfamethoxazole prophylaxis for cesarean section. Am J Obstet Gynecol 1986; 154 (05) 1113-1114
    CrossrefPubMedGoogle Scholar
  • 126 Garcia MHGI, Doyague MJ, Luna S. , et al. Incidence of urinary infection and other infectious complications in antibiotic prophylaxis of cesarean section with ultra-short schedule. III. [Incidencia de infección urinaria y otras complicaciones infecciosas en la profilaxis antibiótica de la cesárea con pauta ultracorta. III] Tokoginecol Pract 1992; 51 (07) 349-356
    PubMedGoogle Scholar
  • 127 Gardella C, Goltra LB, Laschansky E. , et al. High-concentration supplemental perioperative oxygen to reduce the incidence of postcesarean surgical site infection: a randomized controlled trial. Obstet Gynecol 2008; 112 (03) 545-552
    CrossrefPubMedGoogle Scholar
  • 128 Gemer O, Kruchkovich J, Kapustian V. , et al. Short term effects of peritoneal closure at cesarean section: results of a randomized controlled trial. Am J Obstet Gynecol 2006; 195 (06) S111
    PubMedGoogle Scholar
  • 129 Gerstner G, Kofler E, Huber J. Perioperative metronidazole-prophylaxis for cesarian section (author's transl) [in German]. Z Geburtshilfe Perinatol 1980; 184 (06) 418-423
    PubMedGoogle Scholar
  • 130 Ghahiry A, Rezaei F, Karimi Khouzani R, Ashrafinia M. Comparative analysis of long-term outcomes of Misgav Ladach technique cesarean section and traditional cesarean section. J Obstet Gynaecol Res 2012; 38 (10) 1235-1239
    CrossrefPubMedGoogle Scholar
  • 131 Ghongdemath JS, Banale SB. A randomized study comparing non-closure and closure of visceral and parietal peritoneum during cesarean section. J Obstet Gynaecol India 2011; 61 (01) 48-52
    CrossrefPubMedGoogle Scholar
  • 132 Giacalone PL, Daures JP, Vignal J, Herisson C, Hedon B, Laffargue F. Pfannenstiel versus Maylard incision for cesarean delivery: a randomized controlled trial. Obstet Gynecol 2002; 99 (5, Pt 1): 745-750
    PubMedGoogle Scholar
  • 133 Gibbs RS, DeCherney AH, Schwarz RH. Prophylactic antibiotics in cesarean section: a double-blind study. Am J Obstet Gynecol 1972; 114 (08) 1048-1053
    CrossrefPubMedGoogle Scholar
  • 134 Gibbs RS, Hunt JE, Schwarz RH. A follow-up study on prophylactic antibiotics in cesarean section. Am J Obstet Gynecol 1973; 117 (03) 419-422
    CrossrefPubMedGoogle Scholar
  • 135 Gibbs RS, St Clair PJ, Castillo MS, Castaneda YS. Bacteriologic effects of antibiotic prophylaxis in high-risk cesarean section. Obstet Gynecol 1981; 57 (03) 277-282
    PubMedGoogle Scholar
  • 136 Gidiri MF, Ziruma A. A randomized clinical trial evaluating prophylactic single-dose vs prolonged course of antibiotics for caesarean section in a high HIV-prevalence setting. J Obstet Gynaecol 2014; 34 (02) 160-164
    CrossrefPubMedGoogle Scholar
  • 137 Gonen R, Samberg I, Levinski R, Levitan Z, Sharf M. Effect of irrigation or intravenous antibiotic prophylaxis on infectious morbidity at cesarean section. Obstet Gynecol 1986; 67 (04) 545-548
    PubMedGoogle Scholar
  • 138 Gong SP, Guo HX, Zhou HZ, Chen L, Yu YH. Morbidity and risk factors for surgical site infection following cesarean section in Guangdong Province, China. J Obstet Gynaecol Res 2012; 38 (03) 509-515
    CrossrefPubMedGoogle Scholar
  • 139 Gordon HR, Phelps D, Blanchard K. Prophylactic cesarean section antibiotics: maternal and neonatal morbidity before or after cord clamping. Obstet Gynecol 1979; 53 (02) 151-156
    PubMedGoogle Scholar
  • 140 Graham JM, Blanco JD, Oshiro BT, Magee KP, Monga M, Eriksen N. Single-dose ampicillin prophylaxis does not eradicate enterococcus from the lower genital tract. Obstet Gynecol 1993; 81 (01) 115-117
    PubMedGoogle Scholar
  • 141 Grundsell HS, Rizk DE, Kumar RM. Randomized study of non-closure of peritoneum in lower segment cesarean section. Acta Obstet Gynecol Scand 1998; 77 (01) 110-115
    CrossrefPubMedGoogle Scholar
  • 142 Gummerus M. Perioperative short-term prevention of puerperal infections following cesarean section with metronidazole [in German]. Geburtshilfe Frauenheilkd 1984; 44 (09) 570-572
    Article in Thieme ConnectPubMedGoogle Scholar
  • 143 Güngördük K, Asicioglu O, Celikkol O, Ark C, Tekırdağ AI. Does saline irrigation reduce the wound infection in caesarean delivery?. J Obstet Gynaecol 2010; 30 (07) 662-666
    CrossrefPubMedGoogle Scholar
  • 144 Güngördük K, Yildirim G, Ark C. Is routine cervical dilatation necessary during elective caesarean section? A randomised controlled trial. Aust N Z J Obstet Gynaecol 2009; 49 (03) 263-267
    CrossrefPubMedGoogle Scholar
  • 145 Gutiérrez JG, Coló JA, Arreola MS. Comparative trial between traditional cesarean section and Misgav-Ladach technique [in German]. Ginecol Obstet Mex 2008; 76 (02) 75-80
    PubMedGoogle Scholar
  • 146 Guzman MA, Prien SD, Blann DW. Post-cesarean related infection and vaginal preparation with povidone–iodine revisited. Prim Care Update OB/GYNS 2002; 9 (06) 206-209
    CrossrefPubMedGoogle Scholar
  • 147 Haas DM, Pazouki F, Smith RR. , et al. Vaginal cleansing before cesarean delivery to reduce postoperative infectious morbidity: a randomized, controlled trial. Am J Obstet Gynecol 2010; 202 (03) 310.e1-310.e6
    CrossrefPubMedGoogle Scholar
  • 148 Hager WD, Rapp RP, Billeter M, Bradley BB. Choice of antibiotic in nonelective cesarean section. Antimicrob Agents Chemother 1991; 35 (09) 1782-1784
    CrossrefPubMedGoogle Scholar
  • 149 Hager WD, Williamson MM. Effects of antibiotic prophylaxis on women undergoing nonelective cesarean section in a community hospital. J Reprod Med 1983; 28 (10) 687-690
    PubMedGoogle Scholar
  • 150 Hägglund L, Christensen KK, Christensen P, Weström L, Ingemarsson I. Reduced rate of postoperative infections in emergency cesarean section after two doses of cefuroxim perioperatively. A placebo-controlled study. Acta Obstet Gynecol Scand 1989; 68 (03) 201-204
    CrossrefPubMedGoogle Scholar
  • 151 Hamar BD, Saber SB, Cackovic M. , et al. Ultrasound evaluation of the uterine scar after cesarean delivery: a randomized controlled trial of one- and two-layer closure. Obstet Gynecol 2007; 110 (04) 808-813
    CrossrefPubMedGoogle Scholar
  • 152 Harger JH, English DH. Selection of patients for antibiotic prophylaxis in cesarean sections. Am J Obstet Gynecol 1981; 141 (07) 752-758
    CrossrefPubMedGoogle Scholar
  • 153 Hauth JC, Owen J, Davis RO. Transverse uterine incision closure: one versus two layers. Am J Obstet Gynecol 1992; 167 (4, Pt 1): 1108-1111
    CrossrefPubMedGoogle Scholar
  • 154 Hawrylyshyn PA, Bernstein P, Papsin FR. Short-term antibiotic prophylaxis in high-risk patients following cesarean section. Am J Obstet Gynecol 1983; 145 (03) 285-289
    CrossrefPubMedGoogle Scholar
  • 155 Heilmann L, Tauber PF. Short-term prevention with cefoxitin in cesarean section [in German]. Geburtshilfe Frauenheilkd 1984; 44 (12) 792-795
    Article in Thieme ConnectPubMedGoogle Scholar
  • 156 Hidar S, Jennane TM, Bouguizane S, Lassoued L, Bibi M, Khaïri H. The effect of placental removal method at cesarean delivery on perioperative hemorrhage: a randomized clinical trial ISRCTN 49779257. Eur J Obstet Gynecol Reprod Biol 2004; 117 (02) 179-182
    CrossrefPubMedGoogle Scholar
  • 157 Hidar S, Jerbi M, Hafsa A, Slama A, Bibi M, Khaïri H. The effect of uterine incision expansion at caesarean delivery on perioperative haemorrhage: a prospective randomised clinical trial [in French]. Rev Med Liege 2007; 62 (04) 235-238
    PubMedGoogle Scholar
  • 158 Højberg KE, Aagaard J, Laursen H, Diab L, Secher NJ. Closure versus non-closure of peritoneum at cesarean section--evaluation of pain. A randomized study. Acta Obstet Gynecol Scand 1998; 77 (07) 741-745
    CrossrefPubMedGoogle Scholar
  • 159 Huam SH, Lim JM, Raman S. Single-dose antibiotic prophylaxis in women undergoing elective caesarean section. Med J Malaysia 1997; 52 (01) 3-7
    PubMedGoogle Scholar
  • 160 Huchon C, Raiffort C, Chis C, Messaoudi F, Jacquemot MC, Panel P. Caesarean section: closure or non-closure of peritoneum? A randomized trial of postoperative morbidity [in French]. Gynécol Obstét Fertil 2005; 33 (10) 745-749
    CrossrefPubMedGoogle Scholar
  • 161 Hull D, Varner M. Closure of the peritoneal membranes at the time of cesarean section - a prospective randomized study. Paper presented at: Proceedings of 10th Annual Meeting of Society of Perinatal Obstetricians; January 23–27, 1990; Houston, Texas, USA; 1990:119
    PubMedGoogle Scholar
  • 162 Ijarotimi AO, Badejoko OO, Ijarotimi O, Loto OM, Orji EO, Fasubaa OB. Comparison of short versus long term antibiotic prophylaxis in elective caesarean section at the Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria. Niger Postgrad Med J 2013; 20 (04) 325-330
    PubMedGoogle Scholar
  • 163 Imhof NHG, Huch A, Huch R, Zimmerman R. Use of drainage vs no drain for caesarean section. Gynakol Geburtshilfliche Rundsch 2001; (39) 164
    PubMedGoogle Scholar
  • 164 Ismail MA, Nelson KE, Larson P, Moses VK. Selective effect of cefoxitin prophylaxis on post-cesarean-section microbial flora. J Reprod Med 1990; 35 (02) 168-174
    PubMedGoogle Scholar
  • 165 Jaffe R, Altaras M, Cohen I, Ben-Aderet N. Single-dose mezlocillin prophylaxis in emergency cesarean section. Clin Ther 1985; 7 (04) 507-511
    PubMedGoogle Scholar
  • 166 Jaffe R, Altaras M, Loebel R, Ben-Aderet N. Single- versus multiple-dose mezlocillin prophylaxis in emergency cesarean section. Chemotherapy 1986; 32 (02) 173-177
    CrossrefPubMedGoogle Scholar
  • 167 Jaffe R, Loebel R, Altaras M, Ben Aderet N. Perioperative mezlocillin prophylaxis in cesarean section. Clin Ther 1984; 6 (04) 467-474
    PubMedGoogle Scholar
  • 168 Jakobi P, Weissman A, Sigler E, Margolis K, Zimmer EZ. Post-cesarean section febrile morbidity. Antibiotic prophylaxis in low-risk patients. J Reprod Med 1994; 39 (09) 707-710
    PubMedGoogle Scholar
  • 169 Jakobi P, Weissman A, Zimmer EZ, Paldi E. Single-dose cefazolin prophylaxis for cesarean section. Am J Obstet Gynecol 1988; 158 (05) 1049-1052
    CrossrefPubMedGoogle Scholar
  • 170 Juergens S, Maune C, Kezze F, Mohr T, Scheuer K, Mallmann P. A randomized, controlled study comparing the cosmetic outcome of a new wound closure device with Prolene suture closing caesarean wounds. Int Wound J 2011; 8 (04) 329-335
    CrossrefPubMedGoogle Scholar
  • 171 Jyothi S, Vyas NM, Kumar P, Kamath A. Antibiotic prophylaxis for hysterectomy and cesarean section: amoxicillin-clavulanic acid versus cefazolin. J Obstet Gynaecol India 2010; 60 (05) 419-423
    CrossrefPubMedGoogle Scholar
  • 172 Kaimal AJ, Zlatnik MG, Cheng YW. , et al. Effect of a change in policy regarding the timing of prophylactic antibiotics on the rate of postcesarean delivery surgical-site infections. Am J Obstet Gynecol 2008; 199 (03) 310.e1-310.e5
    CrossrefPubMedGoogle Scholar
  • 173 Kalaranjini S, Veena P, Rani R. Comparison of administration of single dose ceftriaxone for elective caesarean section before skin incision and after cord clamping in preventing post-operative infectious morbidity. Arch Gynecol Obstet 2013; 288 (06) 1263-1268
    CrossrefPubMedGoogle Scholar
  • 174 Kamilya G, Seal SL, Mukherji J, Roy H, Bhattacharyya SK, Hazra A. A randomized controlled trial comparing two different antibiotic regimens for prophylaxis at cesarean section. J Obstet Gynaecol India 2012; 62 (01) 35-38
    PubMedGoogle Scholar
  • 175 Kandil M, Sanad Z, Gaber W. Antibiotic prophylaxis at elective cesarean section: a randomized controlled trial in a low resource setting. J Matern Fetal Neonatal Med 2014; 27 (06) 588-591
    CrossrefPubMedGoogle Scholar
  • 176 Kapustian V, Anteby EY, Gdalevich M, Shenhav S, Lavie O, Gemer O. Effect of closure versus nonclosure of peritoneum at cesarean section on adhesions: a prospective randomized study. Am J Obstet Gynecol 2012; 206 (01) 56.e1-56.e4
    CrossrefPubMedGoogle Scholar
  • 177 Karhunen M, Koskela O, Teisala K, Suikkari AM, Mattila J. Prophylaxis and treatment of anaerobic infections following caesarean section with tinidazole. Chemotherapy 1985; 31 (03) 228-236
    CrossrefPubMedGoogle Scholar
  • 178 Kayihura V, Osman NB, Bugalho A, Bergström S. Choice of antibiotics for infection prophylaxis in emergency cesarean sections in low-income countries: a cost-benefit study in Mozambique. Acta Obstet Gynecol Scand 2003; 82 (07) 636-641
    CrossrefPubMedGoogle Scholar
  • 179 Kellum RB, Roberts WE, Harris JB, Khansur N, Morrison JC. Effect of intrauterine antibiotic lavage after cesarean birth on postoperative morbidity. J Reprod Med 1985; 30 (07) 527-529
    PubMedGoogle Scholar
  • 180 Kolben M, Mandoki E, Ulm K, Freitag K. Randomized trial of cefotiam prophylaxis in the prevention of postoperative infectious morbidity after elective cesarean section. Eur J Clin Microbiol Infect Dis 2001; 20 (01) 40-42
    PubMedGoogle Scholar
  • 181 Komoto Y, Koichiro S, Takashi S. , et al. Randomized study of nonclosure or closure of the peritoneum at cesarean delivery in 123 women: the impact of the interval to the next pregnancy. Am J Obstet Gynecol 2005; 193 (06) S126
    PubMedGoogle Scholar
  • 182 Köppel R, Kaehler D, Benz J. The effectiveness of preventive use of antibiotics in Cesarean section with a single dose: comparison of cefotaxime with amoxicillin plus clavulanic acid [in German]. Geburtshilfe Frauenheilkd 1992; 52 (02) 113-116
    Article in Thieme ConnectPubMedGoogle Scholar
  • 183 Kreutner AK, del Bene VE, Delamar D, Huguley V, Harmon PM, Mitchell KS. Perioperative antibiotic prophylaxis is cesarean section. Obstet Gynecol 1978; 52 (03) 279-284
    PubMedGoogle Scholar
  • 184 Kristensen GB, Beiter EC, Mather O. Single-dose cefuroxime prophylaxis in non-elective cesarean section. Acta Obstet Gynecol Scand 1990; 69 (06) 497-500
    CrossrefPubMedGoogle Scholar
  • 185 Kumar SA. Subcutaneous drain versus subcutaneous stitch closure to prevent wound disruption after cesarean section. J Obstet Gynaecol India 2004; 54: 237
    PubMedGoogle Scholar
  • 186 Lal K, Tsomo P. Comparative study of single layer and conventional closure of uterine incision in cesarean section. Int J Gynaecol Obstet 1988; 27 (03) 349-352
    CrossrefPubMedGoogle Scholar
  • 187 Lapas KA, Todorov I. Comparative double-blind study of intravenous metronidazole versus placebo in preventing infection after cesarean section [in Bulgarian]. Akush Ginekol (Sofiia) 1988; 27 (02) 46-49
    PubMedGoogle Scholar
  • 188 Lasley DS, Eblen A, Yancey MK, Duff P. The effect of placental removal method on the incidence of postcesarean infections. Am J Obstet Gynecol 1997; 176 (06) 1250-1254
    CrossrefPubMedGoogle Scholar
  • 189 Lehapa AMTO, Mahapa DH. The comparative efficacy and cost benefit of ceftriaxone versus ampicillin as prophylaxis in patients undergoing caesarean section. Women's Health - into the new millennium Proceedings of the 4th International Scientific Meeting of the Royal College of Obstetricians and Gynaecologists; 1999 1999 October 3–6; Cape Town, South Africa: RCOG; 1999
    PubMedGoogle Scholar
  • 190 Lemus Rocha R, García Gutiérrez LB, Basavilvazo Rodríguez MA, Cruz Avelar A, Peralta Pedrero ML, Hernández Valencia M. Incidence of infected surgical wound and prophylaxis with cefotaxime in cesarean section [in Spanish]. Ginecol Obstet Mex 2005; 73 (10) 537-543
    PubMedGoogle Scholar
  • 191 Leonetti HB, Yun H, O'Leary JA, Greenberg AL. Single vs multiple dose piperacillin in high risk primary cesarean section. Am J Gynecol Health 1989; 3: 195-198
    PubMedGoogle Scholar
  • 192 Leth RA, Møller JK, Thomsen RW, Uldbjerg N, Nørgaard M. Risk of selected postpartum infections after cesarean section compared with vaginal birth: a five-year cohort study of 32,468 women. Acta Obstet Gynecol Scand 2009; 88 (09) 976-983
    CrossrefPubMedGoogle Scholar
  • 193 Levin DK, Gorchels C, Andersen R. Reduction of post-cesarean section infectious morbidity by means of antibiotic irrigation. Am J Obstet Gynecol 1983; 147 (03) 273-277
    CrossrefPubMedGoogle Scholar
  • 194 Lewis DF, Otterson WN, Dunnihoo DR. Antibiotic prophylactic uterine lavage in cesarean section: a double-blind comparison of saline, ticarcillin, and cefoxitin irrigation in indigent patients. South Med J 1990; 83 (03) 274-276
    CrossrefPubMedGoogle Scholar
  • 195 Long WH, Rudd EG, Dillon MB. Intrauterine irrigation with cefamandole nafate solution at cesarean section: a preliminary report. Am J Obstet Gynecol 1980; 138 (7, Pt 1): 755-758
    CrossrefPubMedGoogle Scholar
  • 196 Loong RL, Rogers MS, Chang AM. A controlled trial on wound drainage in caesarean section. Aust N Z J Obstet Gynaecol 1988; 28 (04) 266-269
    CrossrefPubMedGoogle Scholar
  • 197 Louie TJ, Binns BA, Baskett TF, Ross J, Koss J. Cefotaxime, cefazolin, or ampicillin prophylaxis of febrile morbidity in emergency cesarean sections. Clin Ther 1982; 5 (Suppl A): 83-96
    PubMedGoogle Scholar
  • 198 Lumbiganon P, Sirivatanapa P, Prasertchareonsook W, Kumlertkit S, Anansuwanchai J. A randomized controlled trial of augmentin vs cefazolin in emergency cesarean section. Int J Gynecol Obstet 1994; 46: 77
    PubMedGoogle Scholar
  • 199 Lyimo FM, Massinde AN, Kidenya BR, Konje ET, Mshana SE. Single dose of gentamicin in combination with metronidazole versus multiple doses for prevention of post-caesarean infection at Bugando Medical Centre in Mwanza, Tanzania: a randomized, equivalence, controlled trial. BMC Pregnancy Childbirth 2013; 13: 123
    CrossrefPubMedGoogle Scholar
  • 200 Maberry MC, Gilstrap III LC, Bawdon R, Little BB, Dax J. Anaerobic coverage for intra-amnionic infection: maternal and perinatal impact. Am J Perinatol 1991; 8 (05) 338-341
    Article in Thieme ConnectPubMedGoogle Scholar
  • 201 Mackeen AD, Khalifeh A, Fleisher J. , et al; CROSS Consortium. Suture compared with staple skin closure after cesarean delivery: a randomized controlled trial. Obstet Gynecol 2014; 123 (06) 1169-1175
    CrossrefPubMedGoogle Scholar
  • 202 Macones GA, Cleary KL, Parry S. , et al. The timing of antibiotics at cesarean: a randomized controlled trial. Am J Perinatol 2012; 29 (04) 273-276
    Article in Thieme ConnectPubMedGoogle Scholar
  • 203 Magann EF, Chauhan SP, Bufkin L, Field K, Roberts WE, Martin Jr JN. Intra-operative haemorrhage by blunt versus sharp expansion of the uterine incision at caesarean delivery: a randomised clinical trial. BJOG 2002; 109 (04) 448-452
    CrossrefPubMedGoogle Scholar
  • 204 Magann EF, Chauhan SP, Rodts-Palenik S, Bufkin L, Martin Jr JN, Morrison JC. Subcutaneous stitch closure versus subcutaneous drain to prevent wound disruption after cesarean delivery: a randomized clinical trial. Am J Obstet Gynecol 2002; 186 (06) 1119-1123
    CrossrefPubMedGoogle Scholar
  • 205 Magann EF, Dodson MK, Ray MA, Harris RL, Martin Jr JN, Morrison JC. Preoperative skin preparation and intraoperative pelvic irrigation: impact on post-cesarean endometritis and wound infection. Obstet Gynecol 1993; 81 (06) 922-925
    PubMedGoogle Scholar
  • 206 Magann EF, Washburne JF, Harris RL, Bass JD, Duff WP, Morrison JC. Infectious morbidity, operative blood loss, and length of the operative procedure after cesarean delivery by method of placental removal and site of uterine repair. J Am Coll Surg 1995; 181 (06) 517-520
    PubMedGoogle Scholar
  • 207 Magro B, Franchi I, Chehadé A, Berti MA, Coppi G. Controlled clinical study cefurotime in preventive antimicrobial therapy during surgical interventions in obstetrics and gynecology [in Italian]. Clin Ter 1983; 105 (03) 209-214
    PubMedGoogle Scholar
  • 208 Maharaj D, Bagratee JS, Moodley J. Drainage at caesarean section--a randomised prospective study. S Afr J Surg 2000; 38 (01) 9-12
    PubMedGoogle Scholar
  • 209 Mahomed K. A double-blind randomized controlled trial on the use of prophylactic antibiotics in patients undergoing elective caesarean section. Br J Obstet Gynaecol 1988; 95 (07) 689-692
    CrossrefPubMedGoogle Scholar
  • 210 Mallaret MR, Blatier JF, Racinet C, Fauconnier J, Favier M, Micoud M. Economic benefit of using antibiotics prophylactically in cesarean sections with little risk of infection [in French]. J Gynecol Obstet Biol Reprod (Paris) 1990; 19 (08) 1061-1064
    PubMedGoogle Scholar
  • 211 Malomo OO, Kuti O, Orji EO, Ogunniyi SO, Sule SS. A randomised controlled study of non-closure of peritoneum at caesarean section in a Nigerian population. J Obstet Gynaecol 2006; 26 (05) 429-432
    CrossrefPubMedGoogle Scholar
  • 212 Malvasi A, Tinelli A, Farine D. , et al. Effects of visceral peritoneal closure on scar formation at cesarean delivery. Int J Gynaecol Obstet 2009; 105 (02) 131-135
    CrossrefPubMedGoogle Scholar
  • 213 Mansueto GB, Tomaselli F. Antibiotic prophylaxis in non-elective cesarean section with single-dose imipenem versus multiple-dose cefotaxime [in Italian]. Riv Eur Sci Med Farmacol 1989; 11 (01) 65-68
    PubMedGoogle Scholar
  • 214 Mathai M, Ambersheth S, George A. Comparison of two transverse abdominal incisions for cesarean delivery. Int J Gynaecol Obstet 2002; 78 (01) 47-49
    CrossrefPubMedGoogle Scholar
  • 215 Mathelier AC. A comparison of postoperative morbidity following prophylactic antibiotic administration by combined irrigation and intravenous route or by intravenous route alone during cesarean section. J Perinat Med 1992; 20 (03) 177-182
    CrossrefPubMedGoogle Scholar
  • 216 McCowan L, Jackson P. The prophylactic use of metronidazole in caesarean section. N Z Med J 1980; 92 (666) 153-155
    PubMedGoogle Scholar
  • 217 McGregor JA, French JI, Makowski E. Single-dose cefotetan versus multidose cefoxitin for prophylaxis in cesarean section in high-risk patients. Am J Obstet Gynecol 1986; 154 (04) 955-960
    CrossrefPubMedGoogle Scholar
  • 218 Memon S, Qazi RA, Bibi S, Parveen N. Effect of preoperative vaginal cleansing with an antiseptic solution to reduce post caesarean infectious morbidity. J Pak Med Assoc 2011; 61 (12) 1179-1183
    PubMedGoogle Scholar
  • 219 Meyer NL, Hosier KV, Scott K, Lipscomb GH. Cefazolin versus cefazolin plus metronidazole for antibiotic prophylaxis at cesarean section. South Med J 2003; 96 (10) 992-995
    CrossrefPubMedGoogle Scholar
  • 220 Miller RD, Crichton D. Ampicillin prophylaxis in cesarean section. S Afr J Obstet Gynaecol 1968; (06) 69-70
    PubMedGoogle Scholar
  • 221 Mivumbi VN, Little SE, Rulisa S, Greenberg JA. Prophylactic ampicillin versus cefazolin for the prevention of post-cesarean infectious morbidity in Rwanda. Int J Gynaecol Obstet 2014; 124 (03) 244-247
    CrossrefPubMedGoogle Scholar
  • 222 Moodley J, Zeeman DJ. Prophylactic and antimicrobial therapy using lincomycin in patients undergoing emergency caesarean section. S Afr Med J 1981; 59 (25) 911-913
    PubMedGoogle Scholar
  • 223 Moraes Filho OB, Costa CFF. Nonclosure of the visceral and parietal peritoneum at cesarean section. [Nao-fechamento dos peritonios visceral e parietal na operacao cesarianan] Rev Bras Ginecol Obstet 1999; 21 (10) 587-591
    CrossrefPubMedGoogle Scholar
  • 224 Moreira CM, Amaral E. Use of electrocautery for coagulation and wound complications in Caesarean sections. ScientificWorldJournal 2014; 2014: 602375
    PubMedGoogle Scholar
  • 225 Moreira P, Moreau JC, Faye ME. , et al. Comparison of two cesarean techniques: classic versus Misgav Ladach cesarean [in French]. J Gynecol Obstet Biol Reprod (Paris) 2002; 31 (06) 572-576
    PubMedGoogle Scholar
  • 226 Moro M, Andrews M. Prophylactic antibiotics in cesarean section. Obstet Gynecol 1974; 44 (05) 688-692
    PubMedGoogle Scholar
  • 227 Morrison JC, Coxwell WL, Kennedy BS, Schreier PC, Wiser WL, Fish SA. The use of prophylactic antibiotics in patients undergoing cesarean section. Surg Gynecol Obstet 1973; 136 (03) 425-428
    PubMedGoogle Scholar
  • 228 Mothilal M, Thivya R, Anjalakshi C, Ramesh A, Damodharan N. Comparison of effectiveness of azithromycin and cefazolin in post caesarean section infection. Int J Pharm Pharm Sci 2013; 5 (03) 92-94
    PubMedGoogle Scholar
  • 229 Murtha AP, Kaplan AL, Paglia MJ, Mills BB, Feldstein ML, Ruff GL. Evaluation of a novel technique for wound closure using a barbed suture. Plast Reconstr Surg 2006; 117 (06) 1769-1780
    CrossrefPubMedGoogle Scholar
  • 230 Myers V, Weed S, Daskalakis C, Berghella V, Tolosa JE, Baxter J. Absorbable versus metal staples for cesarean delivery skin incision closure: a randomized controlled trial. Am J Obstet Gynecol 2006; 195 (06) S100
    PubMedGoogle Scholar
  • 231 Myles TD, Gooch J, Santolaya J. Obesity as an independent risk factor for infectious morbidity in patients who undergo cesarean delivery. Obstet Gynecol 2002; 100 (5, Pt 1): 959-964
    PubMedGoogle Scholar
  • 232 Nabhan AF. Long-term outcomes of two different surgical techniques for cesarean. Int J Gynaecol Obstet 2008; 100 (01) 69-75
    CrossrefPubMedGoogle Scholar
  • 233 Nagele F, Karas H, Spitzer D. , et al. Closure or nonclosure of the visceral peritoneum at cesarean delivery. Am J Obstet Gynecol 1996; 174 (04) 1366-1370
    CrossrefPubMedGoogle Scholar
  • 234 Naki MM, Api O, Celik H, Kars B, Yaşar E, Unal O. Comparative study of Misgav-Ladach and Pfannenstiel-Kerr cesarean techniques: a randomized controlled trial. J Matern Fetal Neonatal Med 2011; 24 (02) 239-244
    CrossrefPubMedGoogle Scholar
  • 235 Naumann RW, Hauth JC, Owen J, Hodgkins PM, Lincoln T. Subcutaneous tissue approximation in relation to wound disruption after cesarean delivery in obese women. Obstet Gynecol 1995; 85 (03) 412-416
    CrossrefPubMedGoogle Scholar
  • 236 Neuman M, Langer R, Bachar R, Golan A, Bukovsky I, Caspi E. Penicillin-tetracycline prophylaxis in cesarean delivery: prospective and randomized comparison of short and long term therapy. J Perinat Med 1990; 18 (02) 145-148
    CrossrefPubMedGoogle Scholar
  • 237 Ng NK, Sivalingam N. The role of prophylactic antibiotics in caesarean section--a randomised trial. Med J Malaysia 1992; 47 (04) 273-279
    PubMedGoogle Scholar
  • 238 Noyes N, Berkeley AS, Freedman K, Ledger W. Incidence of postpartum endomyometritis following single-dose antibiotic prophylaxis with either ampicillin/sulbactam, cefazolin, or cefotetan in high-risk cesarean section patients. Infect Dis Obstet Gynecol 1998; 6 (05) 220-223
    CrossrefPubMedGoogle Scholar
  • 239 Nuthalapaty FS, Lee CM, Lee JH, Kuper SG, Higdon III HL. A randomized controlled trial of early versus delayed skin staple removal following caesarean section in the obese patient. J Obstet Gynaecol Can 2013; 35 (05) 426-433
    CrossrefPubMedGoogle Scholar
  • 240 Oestreicher M, Oestreicher S, Dudenhausen JW. Prospective study of administering a single-dose prophylactic antibiotic in primarily indicated abdominal cesarean section [in French]. Z Geburtshilfe Perinatol 1987; 191 (01) 12-14
    PubMedGoogle Scholar
  • 241 O'Leary JA, Mullins Jr JH, Andrinopoulos GC. Ampicillin vs. ampicillin-gentamicin prophylaxis in high-risk primary cesarean section. J Reprod Med 1986; 31 (01) 27-30
    PubMedGoogle Scholar
  • 242 Olsen MA, Butler AM, Willers DM, Devkota P, Gross GA, Fraser VJ. Risk factors for surgical site infection after low transverse cesarean section. Infect Control Hosp Epidemiol 2008; 29 (06) 477-484 , discussion 485–486
    CrossrefPubMedGoogle Scholar
  • 243 Opøien HK, Valbø A, Grinde-Andersen A, Walberg M. Post-cesarean surgical site infections according to CDC standards: rates and risk factors. A prospective cohort study. Acta Obstet Gynecol Scand 2007; 86 (09) 1097-1102
    CrossrefPubMedGoogle Scholar
  • 244 Osman B, Abbas A, Ahmed MA, Abubaker MS, Adam I. Prophylactic ceftizoxime for elective cesarean delivery at Soba Hospital, Sudan. BMC Res Notes 2013; 6: 57
    CrossrefPubMedGoogle Scholar
  • 245 Padilla SL, Spence MR, Beauchamp PJ. Single-dose ampicillin for cesarean section prophylaxis. Obstet Gynecol 1983; 61 (04) 463-466
    PubMedGoogle Scholar
  • 246 Parulekar P, Kumar S, Awasthi RT, Tarneja P. A single dose of cefotoxime - as a prophylaxis during caesarean section. J Obstet Gynaecol India 2001; 51 (05) 118-121
    PubMedGoogle Scholar
  • 247 Peterson CM, Medchill M, Gordon DS, Chard HL. Cesarean prophylaxis: a comparison of cefamandole and cefazolin by both intravenous and lavage routes, and risk factors associated with endometritis. Obstet Gynecol 1990; 75 (02) 179-182
    PubMedGoogle Scholar
  • 248 Phelan JP, Pruyn SC. Prophylactic antibiotics in cesarean section: a double-blind study of cefazolin. Am J Obstet Gynecol 1979; 133 (05) 474-478
    CrossrefPubMedGoogle Scholar
  • 249 Pietrantoni M, Parsons MT, O'Brien WF, Collins E, Knuppel RA, Spellacy WN. Peritoneal closure or non-closure at cesarean. Obstet Gynecol 1991; 77 (02) 293-296
    CrossrefPubMedGoogle Scholar
  • 250 Pitt C, Sanchez-Ramos L, Kaunitz AM. Adjunctive intravaginal metronidazole for the prevention of postcesarean endometritis: a randomized controlled trial. Obstet Gynecol 2001; 98 (5, Pt 1): 745-750
    PubMedGoogle Scholar
  • 251 Polk BF, Krache M, Phillippe M. , et al. Randomized clinical trial of perioperative cefoxitin in preventing maternal infection after primary cesarean section. Am J Obstet Gynecol 1982; 142 (08) 983-987
    CrossrefPubMedGoogle Scholar
  • 252 Poonam BB, Banerjee B, Singh SN, Raina A. The Misgav Ladach method: a step forward in the operative technique of caesarean section. Kathmandu Univ Med J (KUMJ) 2006; 4 (02) 198-202
    PubMedGoogle Scholar
  • 253 Racinet C, Mallaret MR, Favier M. , et al. Antibiotic prophylaxis in cesarean sections without high risk of infection. Therapeutic trial of cefotetan versus placebo [in French]. Presse Med 1990; 19 (38) 1755-1758
    PubMedGoogle Scholar
  • 254 Rafique Z, Shibli KU, Russell IF, Lindow SW. A randomised controlled trial of the closure or non-closure of peritoneum at caesarean section: effect on post-operative pain. BJOG 2002; 109 (06) 694-698
    CrossrefPubMedGoogle Scholar
  • 255 Ramsey PS, White AM, Guinn DA. , et al. Subcutaneous tissue reapproximation, alone or in combination with drain, in obese women undergoing cesarean delivery. Obstet Gynecol 2005; 105 (5, Pt 1): 967-973
    CrossrefPubMedGoogle Scholar
  • 256 Rayburn W, Varner M, Galask R, Petzold CR, Piehl E. Comparison of moxalactam and cefazolin as prophylactic antibiotics during cesarean section. Antimicrob Agents Chemother 1985; 27 (03) 337-339
    CrossrefPubMedGoogle Scholar
  • 257 Reckel J, Scheele R. Perioperative antibiotic prophylaxis in cesarean section [Perioperative Antibiotikaprophylaxe bei Kaiserschnitt]. Der Klinikarzt 1985; 14: 1054-1065
    PubMedGoogle Scholar
  • 258 Rehu M, Jahkola M. Prophylactic antibiotics in caesarean section: effect of a short preoperative course of benzyl penicillin or clindamycin plus gentamicin on postoperative infectious morbidity. Ann Clin Res 1980; 12 (02) 45-48
    PubMedGoogle Scholar
  • 259 Reid VC, Hartmann KE, MCMahon M, Fry EP. Vaginal preparation with povidone iodine and postcesarean infectious morbidity: a randomized controlled trial. Obstet Gynecol 2001; 97 (01) 147-152
    PubMedGoogle Scholar
  • 260 Rizk DE, Nsanze H, Mabrouk MH, Mustafa N, Thomas L, Kumar M. Systemic antibiotic prophylaxis in elective cesarean delivery. Int J Gynaecol Obstet 1998; 61 (03) 245-251
    CrossrefPubMedGoogle Scholar
  • 261 Rodriguez AI, Porter K, O'Brien WE. Blunt versus sharp expansion of the uterine incision in low-segment transverse cesarean section. Am J Obstet Gynecol 1994; 171: 1022-1025
    CrossrefPubMedGoogle Scholar
  • 262 Roex AJ, Puyenbroek JI, MacLaren DM, van Geijn HP, Arts NF. A randomized clinical trial of antibiotic prophylaxis in cesarean section: maternal morbidity, risk factors and bacteriological changes. Eur J Obstet Gynecol Reprod Biol 1986; 22 (03) 117-124
    CrossrefPubMedGoogle Scholar
  • 263 Roex AJ, Puyenbroek JI, van Loenen AC, Arts NF. Single- versus three-dose cefoxitin prophylaxis in caesarean section: a randomized clinical trial. Eur J Obstet Gynecol Reprod Biol 1987; 25 (04) 293-298
    CrossrefPubMedGoogle Scholar
  • 264 Rosaschino P, Palmerio G, Ziliani A, Gambarini A, Zambetti E, Bagolan M. Antibiotic prophylaxis in cesarean section: a controlled randomized study of mezlocillin vs. ceftriaxone. [La profilassi antibiotica nel taglio cesareo: mezlocillina vs. cetriaxone. Studio controllato randomizzato] Gionale Italiano do Ostetricia e Ginecologia 1988; 10 (08) 587-588
    PubMedGoogle Scholar
  • 265 Roset E, Boulvain M, Irion O. Nonclosure of the peritoneum during caesarean section: long-term follow-up of a randomised controlled trial. Eur J Obstet Gynecol Reprod Biol 2003; 108 (01) 40-44
    CrossrefPubMedGoogle Scholar
  • 266 Ross L, Mason P, Barnet-Lamb M, Robinson RE, Warren R. Prophylactic metronidazole in patients with ruptured membranes undergoing emergency caesarean section. J Obstet Gynaecol 1984; 5 (01) 32-35
    CrossrefPubMedGoogle Scholar
  • 267 Rothbard MJ, Mayer W, Wystepek A, Gordon M. Prophylactic antibiotics in cesarean section. Obstet Gynecol 1975; 45 (04) 421-424
    PubMedGoogle Scholar
  • 268 Roungsipragarn R, Somboonsub O. Hypertrophic cesarean section scarring: polyglycolic acid and nylon sutures in a randomized trial. J Obstet Gynaecol 2001; 13 (01) 19-21
    PubMedGoogle Scholar
  • 269 Rousseau JA, Girard K, Turcot-Lemay L, Thomas N. A randomized study comparing skin closure in cesarean sections: staples vs subcuticular sutures. Am J Obstet Gynecol 2009; 200 (03) 265.e1-265.e4
    CrossrefPubMedGoogle Scholar
  • 270 Rouzi AA, Khalifa F, Ba'aqeel H, Al-Hamdan HS, Bondagji N. The routine use of cefazolin in cesarean section. Int J Gynaecol Obstet 2000; 69 (02) 107-112
    CrossrefPubMedGoogle Scholar
  • 271 Rudge MV, Atallah AN, Peraçoli JC, Tristão AdaR, Mendonça Neto M. Randomized controlled trial on prevention of postcesarean infection using penicillin and cephalothin in Brazil. Acta Obstet Gynecol Scand 2006; 85 (08) 945-948
    CrossrefPubMedGoogle Scholar
  • 272 Ruiz-Moreno JA, Garcia-Rojas JM, Lozada-Leon JD. Prevention of postcesarean infectious morbidity with a single dose of intravenous metronidazole. Int J Gynaecol Obstet 1991; 34 (03) 217-220
    CrossrefPubMedGoogle Scholar
  • 273 Batioǧlu S, Kuşçu E, Duran EH, Haberal A. One-layer closure of low segment transverse uterine incision by the Lembert technique. J Gynecol Surg 2009; 14 (01) 11-14
    PubMedGoogle Scholar
  • 274 Saha SK, De KC, Bhattacharya PK, Sanyal MK, Pal D. Closure versus non-closure of the visceral peritoneum in gynaec and obstetrics major operations. J Obstet Gynaecol India 2001; 51 (03) 34-36
    PubMedGoogle Scholar
  • 275 Saltzman DH, Eron LJ, Kay HH, Sites JG. Single-dose antibiotic prophylaxis in high-risk patients undergoing cesarean section. Obstet Gynecol 1985; 65 (05) 655-657
    PubMedGoogle Scholar
  • 276 Saltzman DH, Eron LJ, Toy C, Protomastro LJ, Sites JG. Ticarcillin plus clavulanic acid versus cefoxitin in the prophylaxis of infection after cesarean section. Am J Med 1985; 79 (5B) 172-173
    CrossrefPubMedGoogle Scholar
  • 277 Saltzman DH, Eron LJ, Tuomala RE, Protomastro LJ, Sites JG. Single-dose antibiotic prophylaxis in high-risk patients undergoing cesarean section. A comparative trial. J Reprod Med 1986; 31 (08) 709-712
    PubMedGoogle Scholar
  • 278 Saravolatz LD, Lee C, Drukker B. Comparison of intravenous administration with intrauterine irrigation with ceforanide for nonelective cesarean section. Obstet Gynecol 1985; 66 (04) 513-516
    PubMedGoogle Scholar
  • 279 Saunders NJ, Barclay C. Closed suction wound drainage and lower-segment caesarean section. Br J Obstet Gynaecol 1988; 95 (10) 1060-1062
    CrossrefPubMedGoogle Scholar
  • 280 Scarpignato C, Caltabiano M, Condemi V, Mansani FE. Short-term versus long-term cefuroxime prophylaxis in patients undergoing emergency cesarean section. Clin Ther 1982; 5 (02) 186-192
    PubMedGoogle Scholar
  • 281 Schedvins K, Moberg PJ. Prevention of postoperative infection in cesarean section after rupture of the membranes. Int J Gynaecol Obstet 1986; 24 (03) 165-168
    CrossrefPubMedGoogle Scholar
  • 282 Schneid-Kofman N, Sheiner E, Levy A, Holcberg G. Risk factors for wound infection following cesarean deliveries. Int J Gynaecol Obstet 2005; 90 (01) 10-15
    CrossrefPubMedGoogle Scholar
  • 283 Scifres CM, Leighton BL, Fogertey PJ, Macones GA, Stamilio DM. Supplemental oxygen for the prevention of postcesarean infectious morbidity: a randomized controlled trial. Am J Obstet Gynecol 2011; 205 (03) 267.e1-267.e9
    CrossrefPubMedGoogle Scholar
  • 284 Sekhavat L, Dehghani Firouzabadi R, Mojiri P. Effect of expansion technique of uterine incision on maternal blood loss in cesarean section. Arch Gynecol Obstet 2010; 282 (05) 475-479
    CrossrefPubMedGoogle Scholar
  • 285 Shah S, Mazher Y, John IS. Single or triple dose piperacillin prophylaxis in elective cesarean section. Int J Gynaecol Obstet 1998; 62 (01) 23-29
    CrossrefPubMedGoogle Scholar
  • 286 Shahin AY, Hameed DA. Does visceral peritoneal closure affect post-cesarean urinary symptoms? A randomized clinical trial. Int Urogynecol J Pelvic Floor Dysfunct 2010; 21 (01) 33-41
    CrossrefPubMedGoogle Scholar
  • 287 Shahin AY, Osman AM. Parietal peritoneal closure and persistent postcesarean pain. Int J Gynaecol Obstet 2009; 104 (02) 135-139
    CrossrefPubMedGoogle Scholar
  • 288 Shrestha A, Napit J, Neupane B, Sedhai LB. A randomized trial comparing skin closure in cesarean section: interrupted suture with nylon vs subcuticular suture with No ‘1’ polyfilament. J Nepal Health Res Counc 2013; 11 (25) 240-243
    PubMedGoogle Scholar
  • 289 Sokolowski H, Canzler E, Brötzmann C. Follow-up and wound healing following cesarean section with prophylactic use of Vagimid in comparison with the puerperal course without the use of Vagimid [in German]. Zentralbl Gynakol 1989; 111 (07) 461-465 , discussion 466–468
    PubMedGoogle Scholar
  • 290 Sokolowski VH, Canzler E, Brotzmann C. Follow-up and wound healing following cesarean section with prophylactic use of Vagimid in comparison with the puerperal course without the use of Vagimid [in German]. Zentralbl Gynakol 1989; 111 (07) 461-465 ; discussion 466–468
    PubMedGoogle Scholar
  • 291 Soper DE, Brockwell NJ, Dalton HP. The importance of wound infection in antibiotic failures in the therapy of postpartum endometritis. Surg Gynecol Obstet 1992; 174 (04) 265-269
    PubMedGoogle Scholar
  • 292 Spinnato JA, Youkilis B, Cook VD, Pietrantoni M, Clark AL, Gall SA. Antibiotic prophylaxis at cesarean delivery. J Matern Fetal Med 2000; 9 (06) 348-350
    PubMedGoogle Scholar
  • 293 Stafford MK, Pitman MC, Nanthakumaran N, Smith JR. Blunt-tipped versus sharp-tipped needles: wound morbidity. J Obstet Gynaecol 1998; 18 (01) 18-19
    CrossrefPubMedGoogle Scholar
  • 294 Stage AH, Glover DD, Vaughan JE. Low-dose cephradine prophylaxis in obstetric and gynecologic surgery. J Reprod Med 1982; 27 (03) 113-119
    PubMedGoogle Scholar
  • 295 Stamilio DM, Scifres CM. Extreme obesity and postcesarean maternal complications. Obstet Gynecol 2014; 124 (2, Pt 1): 227-232
    CrossrefPubMedGoogle Scholar
  • 296 Starr RV, Zurawski J, Ismail M. Preoperative vaginal preparation with povidone-iodine and the risk of postcesarean endometritis. Obstet Gynecol 2005; 105 (5, Pt 1): 1024-1029
    CrossrefPubMedGoogle Scholar
  • 297 Stiver HG, Forward KR, Livingstone RA. , et al. Multicenter comparison of cefoxitin versus cefazolin for prevention of infectious morbidity after nonelective cesarean section. Am J Obstet Gynecol 1983; 145 (02) 158-163
    CrossrefPubMedGoogle Scholar
  • 298 Studziński Z. The Misgav-Ladach method for cesarean section compared to the Pfannenstiel technique [in Polish]. Ginekol Pol 2002; 73 (08) 672-676
    PubMedGoogle Scholar
  • 299 Subramaniam A, Jauk VC, Figueroa D, Biggio JR, Owen J, Tita AT. Risk factors for wound disruption following cesarean delivery. J Matern Fetal Neonatal Med 2014; 27 (12) 1237-1240
    CrossrefPubMedGoogle Scholar
  • 300 Sullivan SA, Smith T, Chang E, Hulsey T, Vandorsten JP, Soper D. Administration of cefazolin prior to skin incision is superior to cefazolin at cord clamping in preventing postcesarean infectious morbidity: a randomized, controlled trial. Am J Obstet Gynecol 2007; 196 (05) 455.e1-455.e5
    CrossrefPubMedGoogle Scholar
  • 301 Szalontay AS. Antibiotic prophylaxis in cesarean section [in Romanian]. Rev Med Chir Soc Med Nat Iasi 1997; 101 (1–2): 156-159
    PubMedGoogle Scholar
  • 302 Sziller I, Karovits J, Erdosi F, Beke A, Oszoli G. Postoperative infectious morbidity after perioperative ampicillin/sulbactam prophylaxis in women undergoing elective caesarean section. Magyar Norvosok Lapja 1994; 57 (02) 101-104
    PubMedGoogle Scholar
  • 303 Tan PC, Mubarak S, Omar SZ. Absorbable versus nonabsorbable sutures for subcuticular skin closure of a transverse suprapubic incision. Int J Gynaecol Obstet 2008; 103 (02) 179-181
    CrossrefPubMedGoogle Scholar
  • 304 Theodoridis TD, Chatzigeorgiou KN, Zepiridis L. , et al. A prospective randomized study for evaluation of wound retractors in the prevention of incision site infections after cesarean section. Clin Exp Obstet Gynecol 2011; 38 (01) 57-59
    PubMedGoogle Scholar
  • 305 Thigpen BD, Hood WA, Chauhan S. , et al. Timing of prophylactic antibiotic administration in the uninfected laboring gravida: a randomized clinical trial. Am J Obstet Gynecol 2005; 192 (06) 1864-1868 , discussion 1868–1871
    CrossrefPubMedGoogle Scholar
  • 306 Tita AT, Owen J, Stamm AM, Grimes A, Hauth JC, Andrews WW. Impact of extended-spectrum antibiotic prophylaxis on incidence of postcesarean surgical wound infection. Am J Obstet Gynecol 2008; 199 (03) 303.e1-303.e3
    CrossrefPubMedGoogle Scholar
  • 307 Tita AT, Hauth JC, Grimes A, Owen J, Stamm AM, Andrews WW. Decreasing incidence of postcesarean endometritis with extended-spectrum antibiotic prophylaxis. Obstet Gynecol 2008; 111 (01) 51-56
    CrossrefPubMedGoogle Scholar
  • 308 Tosun M, Sakinci M, Celik H. , et al. A randomized controlled study investigating the necessity of routine cervical dilatation during elective cesarean section. Arch Gynecol Obstet 2011; 284 (01) 85-89
    CrossrefPubMedGoogle Scholar
  • 309 Tully JL, Klapholz H, Baldini LM, Friedland GH. Perioperative use of cefoxitin in primary cesarean section. J Reprod Med 1983; 28 (12) 827-832
    PubMedGoogle Scholar
  • 310 Tuncer S, Çapar M, Yosunkaya A, Tavlan A, Otelcioglu S. Closure versus nonclosure of peritoneum at cesarean section: Evaluation of postoperative pain. Pain Clin 2003; 15 (01) 29-33
    CrossrefPubMedGoogle Scholar
  • 311 Turner MJ, Egan DM, Qureshi WA. , et al. Use of cephradine prophylaxis of infection after caesarean section: stepwise logistic regression analysis of relevant factors. J Obstet Gynaecol 1990; 10 (03) 204-209
    CrossrefPubMedGoogle Scholar
  • 312 Tuuli MG, Odibo AO, Fogertey P, Roehl K, Stamilio D, Macones GA. Utility of the bladder flap at cesarean delivery: a randomized controlled trial. Obstet Gynecol 2012; 119 (04) 815-821
    CrossrefPubMedGoogle Scholar
  • 313 Tzingounis V, Makris N, Zolotas J, Michalas S, Aravantinos D. Cefuroxime prophylaxis in caesarean section. Pharmatherapeutica 1982; 3 (02) 140-142
    PubMedGoogle Scholar
  • 314 Ujah IAO, Olarewaju RS, Otubu JAM. Prophylactic amoxicillin-clavulanic acid in elective cesarean section. Curr Ther Res Clin Exp 1992; 52: 647-651
    CrossrefPubMedGoogle Scholar
  • 315 van der Linden MC, van Erp EJ, Ruijs GJ, Holm JP. A prospective randomized study comparing amoxycillin/clavulanate with cefuroxime plus metronidazole for perioperative prophylaxis in gynaecological surgery. Eur J Obstet Gynecol Reprod Biol 1993; 50 (02) 141-145
    CrossrefPubMedGoogle Scholar
  • 316 Ventolini G, Neiger R, McKenna D. Decreasing infectious morbidity in cesarean delivery by changing gloves. J Reprod Med 2004; 49 (01) 13-16
    PubMedGoogle Scholar
  • 317 Villeneuve MG, Khalifé S, Marcoux S, Blanchet P. Surgical staples in cesarean section: a randomized controlled trial. Am J Obstet Gynecol 1990; 163 (5, Pt 1): 1641-1646
    CrossrefPubMedGoogle Scholar
  • 318 von Mandach U, Huch R, Malinverni R, Huch A. Ceftriaxone (single dose) versus cefoxitin (multiple doses): success and failure of antibiotic prophylaxis in 1052 cesarean sections. J Perinat Med 1993; 21 (05) 385-397
    CrossrefPubMedGoogle Scholar
  • 319 von Rechenberg KN. Use of a stapler instrument for hysterotomy in cesarean section [in German]. Z Geburtshilfe Perinatol 1990; 194 (02) 85-89
    PubMedGoogle Scholar
  • 320 Voto LS, Benoliel LA, Amadora Muñiz A, Trepat A, Balsechi EE, Margulies M. Prophylaxis of post cesarean section puerperal infection with the using of cefoxitin antibiotics. [Profilaxis de la infección puerperal post-cesarea mediante el uso del antibiótico cefoxitina: I - Resultados de su empleo valorados a través del cultivo sistemático pre, intra y postquirúrgico] Obstet Ginecol Lat Am 1986; 44: 419-424
    PubMedGoogle Scholar
  • 321 Wallace RL, Eglinton GS, Yonekura ML, Wallace TM. Extraperitoneal cesarean section: a surgical form of infection prophylaxis?. Am J Obstet Gynecol 1984; 148 (02) 172-177
    CrossrefPubMedGoogle Scholar
  • 322 Wallin G, Fall O. Modified Joel-Cohen technique for caesarean delivery. Br J Obstet Gynaecol 1999; 106 (03) 221-226
    CrossrefPubMedGoogle Scholar
  • 323 Walss Rodriguez R, Avila Esparza M. Prophylactic antimicrobial therapy in cesarean section. Ginecologia y obstetricia de Mexico 1990; 58: 79-83
    PubMedGoogle Scholar
  • 324 Ward HR, Jennings OG, Potgieter P, Lombard CJ. Do plastic adhesive drapes prevent post caesarean wound infection?. J Hosp Infect 2001; 47 (03) 230-234
    CrossrefPubMedGoogle Scholar
  • 325 Wax JR, Hersey K, Philput C. , et al. Single dose cefazolin prophylaxis for postcesarean infections: before vs. after cord clamping. J Matern Fetal Med 1997; 6 (01) 61-65
    PubMedGoogle Scholar
  • 326 Weerawetwat W, Buranawanich S, Kanawong M. Closure vs non-closure of the visceral and parietal peritoneum at cesarean delivery: 16 year study. J Med Assoc Thai 2004; 87 (09) 1007-1011
    PubMedGoogle Scholar
  • 327 Weissberg SM, Edwards NL, O'Leary JA. Prophylactic antibiotics in cesarean section. Obstet Gynecol 1971; 38 (02) 290-293
    PubMedGoogle Scholar
  • 328 Wells M, McCullough W, Rymer J. Antibiotic prophylaxis in emergency cesarean section. Int J Gynecol Obstet 1994; 46: 77
    PubMedGoogle Scholar
  • 329 Westen EH, Kolk PR, van Velzen CL. , et al. Single-dose compared with multiple day antibiotic prophylaxis for cesarean section in low-resource settings, a randomized controlled, noninferiority trial. Acta Obstet Gynecol Scand 2015; 94 (01) 43-49
    CrossrefPubMedGoogle Scholar
  • 330 Williams N, Crisp C, Glover M, Downing C, McKenna D. 676: Randomized controlled trial evaluating the effect of variable FiO2 on cesarean delivery surgical site infection. Am J Obstet Gynecol 2009; 201 (06) S244
    PubMedGoogle Scholar
  • 331 Witt A, Döner M, Petricevic L. , et al. Antibiotic prophylaxis before surgery vs after cord clamping in elective cesarean delivery: a double-blind, prospective, randomized, placebo-controlled trial. Arch Surg 2011; 146 (12) 1404-1409
    PubMedGoogle Scholar
  • 332 Wong R, Gee CL, Ledger WJ. Prophylactic use of cefazolin in monitored obstetric patients undergoing cesarean section. Obstet Gynecol 1978; 51 (04) 407-411
    CrossrefPubMedGoogle Scholar
  • 333 Work Jr BA. Role of preventive antibiotics in patients undergoing cesarean section. South Med J 1977; 70 (Suppl. 01) 44-45
    CrossrefPubMedGoogle Scholar
  • 334 Wu Y. Prevention of post-operative infection by using antibiotics of 217 cases of cesarean section [in Chinese]. Zhonghua Fu Chan Ke Za Zhi 1992; 27 (02) 73-75 , 123
    PubMedGoogle Scholar
  • 335 Xavier P, Ayres-De-Campos D, Reynolds A, Guimarães M, Costa-Santos C, Patrício B. The modified Misgav-Ladach versus the Pfannenstiel-Kerr technique for cesarean section: a randomized trial. Acta Obstet Gynecol Scand 2005; 84 (09) 878-882
    CrossrefPubMedGoogle Scholar
  • 336 Yasmin S, Sadaf J, Fatima N. Impact of methods for uterine incision closure on repeat caesarean section scar of lower uterine segment. J Coll Physicians Surg Pak 2011; 21 (09) 522-526
    PubMedGoogle Scholar
  • 337 Yildirim G, Güngördük K, Asicioğlu O. , et al. Does vaginal preparation with povidone-iodine prior to caesarean delivery reduce the risk of endometritis? A randomized controlled trial. J Matern Fetal Neonatal Med 2012; 25 (11) 2316-2321
    CrossrefPubMedGoogle Scholar
  • 338 Yildirim G, Gungorduk K, Guven HZ. , et al. When should we perform prophylactic antibiotics in elective cesarean cases?. Arch Gynecol Obstet 2009; 280 (01) 13-18
    CrossrefPubMedGoogle Scholar
  • 339 Yip SK, Lau TK, Rogers MS. A study on prophylactic antibiotics in cesarean sections--is it worthwhile?. Acta Obstet Gynecol Scand 1997; 76 (06) 547-549
    CrossrefPubMedGoogle Scholar
  • 340 Young R, Platt L, Ledger W. Prophylactic cefoxitin in cesarean section. Surg Gynecol Obstet 1983; 157 (01) 11-14
    PubMedGoogle Scholar
  • 341 Zhang LJ, Zhu FF, Wang CH, Fu SX. Clinical analysis of 318 cases of new-mode cesarean section. Bull Hunan Med Univ 2000; 25 (05) 495-498
    PubMedGoogle Scholar
  • 342 Ziogos E, Tsiodras S, Matalliotakis I, Giamarellou H, Kanellakopoulou K. Ampicillin/sulbactam versus cefuroxime as antimicrobial prophylaxis for cesarean delivery: a randomized study. BMC Infect Dis 2010; 10: 341
    CrossrefPubMedGoogle Scholar
  • 343 van ʼt Hooft J, Duffy JM, Daly M. , et al; Global Obstetrics Network (GONet). A core outcome set for evaluation of interventions to prevent preterm birth. Obstet Gynecol 2016; 127 (01) 49-58
    CrossrefPubMedGoogle Scholar
  • 344 Ross S. Composite outcomes in randomized clinical trials: arguments for and against. Am J Obstet Gynecol 2007; 196 (02) 119.e1-119.e6
    CrossrefPubMedGoogle Scholar