J Pediatr Neurol
DOI: 10.1055/s-0039-1692139
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Persistent Fetal Trigeminal Artery with Septopreoptic Holoprosencephaly: Report of an Unusual Association

Sunilkumar D.
1  Department of Radio-Diagnosis, Jawaharlal Institute of Postgraduate Medical Education & Research (JIPMER), Pondicherry, Tamil Nadu, India
,
1  Department of Radio-Diagnosis, Jawaharlal Institute of Postgraduate Medical Education & Research (JIPMER), Pondicherry, Tamil Nadu, India
,
Kiran M.
1  Department of Radio-Diagnosis, Jawaharlal Institute of Postgraduate Medical Education & Research (JIPMER), Pondicherry, Tamil Nadu, India
,
Subathra A.
1  Department of Radio-Diagnosis, Jawaharlal Institute of Postgraduate Medical Education & Research (JIPMER), Pondicherry, Tamil Nadu, India
› Author Affiliations
Further Information

Publication History

03 January 2019

15 April 2019

Publication Date:
04 June 2019 (online)

Abstract

Septopreoptic holoprosencephaly (HPE) is a type of HPE characterized by failure of separation of the septal and preoptic regions. Vascular anomalies associated with septopreoptic HPE include twig-like cerebral vessels and azygos anterior cerebral artery, the latter common to all forms of HPE. Here, we describe an 8-year-old boy presenting with developmental delay and abnormal movements who was found to have septopreoptic HPE associated with persistent trigeminal artery in magnetic resonance neuroimaging. This persistence of fetal trigeminal artery in HPE provides a further understanding of the pathogenesis of HPE.