Am J Perinatol 2020; 37(01): 025-029
DOI: 10.1055/s-0039-1694728
SMFM 2019
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Pregnancy Outcomes in Women with Incidentally Detected Unicornuate Uteri

Kathy C. Matthews
1  Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, NewYork-Presbyterian Hospital/Weill Cornell Medical Center, New York
,
Stephen T. Chasen
1  Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, NewYork-Presbyterian Hospital/Weill Cornell Medical Center, New York
› Author Affiliations
Further Information

Publication History

15 May 2019

28 June 2019

Publication Date:
14 August 2019 (online)

Abstract

Objective To estimate the incidence of adverse pregnancy outcomes in women with incidentally detected unicornuate uteri.

Study Design This is a descriptive study. Database review identified patients with unicornuate uteri and singleton pregnancies at ≥12 weeks' gestation. Patients were excluded if the diagnosis of unicornuate uterus was made after a midtrimester loss or preterm delivery. Records were reviewed to obtain clinical outcomes. Chi-square test, Fisher's exact test, and Mann–Whitney U-test were used for statistical analysis.

Results Forty patients with 67 pregnancies were included. Most diagnoses were made during infertility work-up (76.2%). There was one midtrimester loss (1.5%). In the remaining 66 pregnancies, median gestational age at delivery was 38 weeks. There were 20 (30.3%) preterm births, 9 (13.6%) spontaneous preterm births, and 11 (16.7%) indicated preterm births. Women with indicated preterm births were more likely to have placental abnormalities. Of the available placental pathology, 45.2% had histological lesions of malperfusion. Cesarean delivery was performed in 77.3% of cases.

Conclusion Most women with incidentally detected unicornuate uteri gave birth at term. More than half the preterm births were indicated, with relatively high rates of placental abnormalities. In patients without a poor obstetrical history, rates of midtrimester loss and spontaneous preterm birth were lower than previously described.