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J Pediatr Intensive Care 2020; 09(02): 081-086
DOI: 10.1055/s-0039-3400466
Original Article
Georg Thieme Verlag KG Stuttgart · New York

Human Rhinovirus/Enterovirus in Pediatric Acute Respiratory Distress Syndrome

Michele E. Smith
1   Department of Pediatrics, Columbia University Medical Center, New York-Presbyterian Children's Hospital, New York, United States
,
Patrick T. Wilson 
1   Department of Pediatrics, Columbia University Medical Center, New York-Presbyterian Children's Hospital, New York, United States
› Author Affiliations Funding None.
Further Information

Publication History

16 September 2019

12 October 2019

Publication Date:
21 November 2019 (online)

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Abstract

The role of human rhinovirus/enterovirus (HRV/HEV) in severe lower respiratory tract infections remains unclear. We characterized the respiratory status of children admitted to a large academic pediatric intensive care unit (PICU) who tested positive for only HRV/HEV. One hundred and fifty-five children met inclusion criteria with 62% requiring positive pressure respiratory support of 5 cm of water pressure or more within the first 24 hours of admission. Among them, 34% had SaO2 to FiO2 ratios of 264 or less with 22 patients (14%) meeting criteria for pediatric acute respiratory distress syndrome. HRV/HEV is associated with significant respiratory disease in children admitted to the PICU.

Keywords

rhinovirus - enterovirus - pediatric intensive care units - pediatric acute respiratory distress syndrome
 

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