Abstract
Infantile colic is a common problem observed within the first 3 months of life in
infants and is a common cause of crying among infants. Migraine is a common cause
of recurrent primary headaches during childhood. The pathogenesis of migraine and
colic has remained unknown, but various factors seem to be involved. Patients with
migraine may have a medical history of infantile colic, and infantile colic is considered
an early manifestation of migraine. In this study, we investigate the frequency of
history of infantile colic in 6- to 14-year-old children with migraines. In this case–control
study, 80 children with the diagnosis of migraine and 100 children without migraine,
all within the age range of 6 to 14 years, were included. A checklist was completed
for each person about the background information and history of infantile colic as
well as the history of migraine in parents. Among the children with migraine, 92.5%,
and in the control group, 10%, had a familial history of migraine. Also, among the
children with migraine, 61.25%, and in the control group, 4%, had a history of infantile
colic. The obtained results showed that the frequency of a history of infantile colic
was significantly higher in the case group than in the control group. This study provides
some evidence regarding the presence of association between infantile colic as well
as the familial history of migraines and developing migraines in the future. However,
due to some limitations of the retrospective manner of the study, the results should
be completed with future studies.
Keywords
infantile colic - migraine - child
