Semin Plast Surg 2021; 35(03): 153-158
DOI: 10.1055/s-0041-1731460
Review Article

Updates in Diabetic Wound Healing, Inflammation, and Scarring

Nina Dasari
1  Division of Plastic Surgery, Department of Surgery, Baylor College of Medicine, Houston, Texas
,
Austin Jiang
1  Division of Plastic Surgery, Department of Surgery, Baylor College of Medicine, Houston, Texas
,
Anna Skochdopole
1  Division of Plastic Surgery, Department of Surgery, Baylor College of Medicine, Houston, Texas
,
Jayer Chung
2  Division of Vascular Surgery, Department of Surgery, Baylor College of Medicine, Houston, Texas
,
Edward M. Reece
1  Division of Plastic Surgery, Department of Surgery, Baylor College of Medicine, Houston, Texas
3  Division of Plastic Surgery, Department of Surgery, Texas Children's Hospital, Houston, Texas
,
Joshua Vorstenbosch
4  Division of Plastic Surgery, Department of Surgery, McGill University, Montreal, Canada
,
Sebastian Winocour
1  Division of Plastic Surgery, Department of Surgery, Baylor College of Medicine, Houston, Texas
› Author Affiliations

Abstract

Diabetic patients can sustain wounds either as a sequelae of their disease process or postoperatively. Wound healing is a complex process that proceeds through phases of inflammation, proliferation, and remodeling. Diabetes results in several pathological changes that impair almost all of these healing processes. Diabetic wounds are often characterized by excessive inflammation and reduced angiogenesis. Due to these changes, diabetic patients are at a higher risk for postoperative wound healing complications. There is significant evidence in the literature that diabetic patients are at a higher risk for increased wound infections, wound dehiscence, and pathological scarring. Factors such as nutritional status and glycemic control also significantly influence diabetic wound outcomes. There are a variety of treatments available for addressing diabetic wounds.



Publication History

Publication Date:
15 July 2021 (online)

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