CC BY 4.0 · Journal of Child Science 2021; 11(01): e296-e298
DOI: 10.1055/s-0041-1736477
Case Report

Hemolytic Anemia and Hypoxic Brain Injury following Mothball Ingestion in a G6PD Nondeficient Infant: A Case Report

1   Department of Pediatrics, Mahatma Gandhi Institute of Medical Sciences, Sevagram, Wardha, Maharashtra, India
,
Anuragsingh B. Chandel
2   Department of Paediatrics, Mahatma Gandhi Institute of Medical Sciences, Sevagram, Wardha, Maharashtra, India
,
Ravi Varma
2   Department of Paediatrics, Mahatma Gandhi Institute of Medical Sciences, Sevagram, Wardha, Maharashtra, India
,
Smita Jategaonkar
2   Department of Paediatrics, Mahatma Gandhi Institute of Medical Sciences, Sevagram, Wardha, Maharashtra, India
,
Manish Jain
2   Department of Paediatrics, Mahatma Gandhi Institute of Medical Sciences, Sevagram, Wardha, Maharashtra, India
› Author Affiliations

Abstract

Mothballs are a common household item used as repellents and deodorizers. They are potential hazards and rare agents of poisoning in children. They are composed mainly of naphthalene, camphor, and 1, 4-dichlorobenzene in varying amounts depending on the manufacturers. It is essential to rule out poisoning by naphthalene in children presenting with hemolysis by eliciting a proper history. Since mothballs are readily available at home, children are drawn to it because of its attractive color and its consumption is a likely possibility. This is a case of ingestional naphthalene poisoning in a 1-year-old glucose 6-phosphate dehydrogenase nondeficient male child who presented with altered sensorium and hemolytic anemia. The child developed methemoglobinemia and sustained hypoxic brain injury. He was successfully managed by oral ascorbic acid, blood transfusion, and requisite supportive treatments. We report a case of naphthalene toxicity with hemolytic anemia and hypoxic brain damage to highlight the possibility of naphthalene poisoning in young children presenting with hemolytic anemia.



Publication History

Received: 29 July 2021

Accepted: 30 August 2021

Article published online:
22 November 2021

© 2021. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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  • References

  • 1 Tshiamo W. Paraffin (kerosene)* poisoning in under-five children: a problem of developing countries. Int J Nurs Pract 2009; 15 (03) 140-144
  • 2 Kumar S, Kavitha TK, Angurana SK. Kerosene, camphor, and naphthalene poisoning in children. Indian J Crit Care Med 2019; 23 (04, Suppl 4): S278-S281
  • 3 Sudakin DL, Stone DL, Power L. Naphthalene mothballs: emerging and recurring issues and their relevance to environmental health. Curr Top Toxicol 2011; 7: 13-19
  • 4 Ekambaram S, Chandan Kumar KM, Mahalingam V. Acute kidney injury: a rare complication of mothball (naphthalene) poisoning. Saudi J Kidney Dis Transpl 2017; 28 (06) 1412-1415
  • 5 Uthuman AAA, Jayasinghe CS, Fernando AHN. Acute intravascular hemolysis due to naphthalene toxicity: a case report. J Med Case Reports 2019; 13 (01) 91
  • 6 Rahman MM, Mogni Mowla SG, Rahim A, Chowdhury FR, Jahan S, Hasan MN. Severe haemolytic anaemia due to ingestion of naphthalene (mothball) containing coconut oil. J Coll Physicians Surg Pak 2012; 22 (11) 740-741
  • 7 Kundra TS, Bhutatani V, Gupta R, Kaur P. Naphthalene poisoning following ingestion of mothballs: a case report. J Clin Diagn Res 2015; 9 (08) UD01-UD02
  • 8 Sahu KK, Dhibar DP, Gautam A, Kumar Y, Varma SC. Role of ascorbic acid in the treatment of methemoglobinemia. Turk J Emerg Med 2016; 16 (03) 119-120