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Synfacts 2022; 18(03): 0326
DOI: 10.1055/s-0041-1737839
Chemistry in Medicine and Biology

A Ring-Expansion Strategy Enables the Discovery of Spiro cRAF Inhibitor SHR902275

Authors

    Contributor(s):

  • Dirk Trauner

  • Julian Maximilian Feilner

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Key words

RAF inhibitor - spirocyclization - Beckmann rearrangement


Publication History

Article published online:
16 February 2022

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