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Synlett 1998; 1998(2): 147-148
DOI: 10.1055/s-1998-1604
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Easy Microwave Assisted Deprotection of N-Boc Derivatives

Jorge G. Siro* , Justina Martín, José L. García-Navío, Modesto J. Remuiñan, Juan J. Vaquero
  • *Departamento de Química Orgánica, Universidad de Alcalá, 28871 Alcalá de Henares, Madrid, Spain; Fax 341 8854686; E-mail: qojlgn@quimor.alcala.es
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Publication History

Publication Date:
31 December 2000 (online)

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A simple and efficient method for the cleavage of tert-butoxycarbonyl amides and amines is described, which takes place on silica gel under microwave irradiation.

microwave irradiation - N-Boc deprotection - silica gel