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J Reconstr Microsurg 2001; 17(1): 039-044
DOI: 10.1055/s-2001-12687
DOI: 10.1055/s-2001-12687
Basic Fibroblast Growth Factor Induced Angiogenesis and Prefabricated Flap Survival
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Publication History
Publication Date:
31 December 2001 (online)
ABSTRACT
Prefabrication of a latissimus dorsi myocutaneous flap was performed in adult male Landrace pigs. Gelfoam sponges were used as a delivery system for basic fibroblast growth factor (bFGF) at the muscle-subcutaneous tissue interface. Skin survival and angiogenesis were augmented in the growth-factor-treated animals. These data support the use of basic fibroblast growth factor to enhance flap prefabrication.
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