Normal Perinatal Mortality in Type 1 Diabetes Mellitus in a Series of 300 Consecutive Pregnancy Outcomes

Bernice R. Wylie; Jason Kong; Sharon E. Kozak; Colleen J. Marshall; Suet On Tong; David M. Thompson

doi:10.1055/s-2002-28499

American Journal of Perinatology, Table of Contents

Am J Perinatol 2002; 19(4): 169-176
DOI: 10.1055/s-2002-28499

Normal Perinatal Mortality in Type 1 Diabetes Mellitus in a Series of 300 Consecutive Pregnancy Outcomes

Bernice R. Wylie^1, ² , Jason Kong^2, ³ , Sharon E. Kozak¹ , Colleen J. Marshall¹ , Suet On Tong¹ , David M. Thompson^1, ²

¹British Columbia Women's Hospital, British Columbia, Canada
²University of British Columbia, British Columbia, Canada
³Vancouver Hospital, British Columbia, Canada

Abstract

ABSTRACT

Reports of outcomes of pregnancy in women with type 1 diabetes have consistently found increased perinatal mortality and morbidity. The primary objective of our study was to compare the perinatal mortality rate in type 1 diabetic pregnancies with that of the general population. The secondary objective was to compare the morbidities in these groups. A series of 247 women with type 1 diabetes had 300 consecutive pregnancy outcomes analyzed over a 10-year period. They were compared with the control population from the same hospital. Perinatal mortality was 6.6/1000 (95% CI, 0-17), which was significantly lower than the control population rate of 31/1000. There was an increased incidence of morbidity including maternal hypertension, caesarian section, preterm delivery, birth injury, large for gestational age infants, admissions to neonatal intensive care, neonatal hypoglycemia, and phototherapy. Pregnancies in type 1 diabetes can be associated with a normal perinatal mortality rate although morbidity remains elevated compared with controls.

KEYWORDS

Type 1 diabetes mellitus - fetal/maternal complications - pregnancy

Full Text

References

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