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Am J Perinatol 2004; 21(5): 295-298
DOI: 10.1055/s-2004-829871
Copyright © 2004 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA.

Advanced Gastric Cancer and a Concomitant Pregnancy Associated with Disseminated Intravascular Coagulation

Takumi Kurabayashi1 , Keisuke Isii1 , Mina Suzuki1 , Koichi Takakuwa1 , Yasuhiko Shibazaki2 , Tsunenori Ozawa3 , Rintaro Narisawa4 , Naoto Sekizuka5 , Kenichi Tanaka1
  • 1Department of Obstetrics and Gynecology, Niigata University Hospital, Niigata, Japan
  • 2Department of Internal Medicine I, Niigata University Hospital, Niigata, Japan
  • 3Department of Neurosurgery, Niigata University Hospital, Niigata, Japan
  • 4Department of Endoscopy, Niigata University Hospital, Niigata, Japan
  • 5Department of Endoscopy, Sikizuka Clinic, Niigata, Japan
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Publication Date:
01 July 2004 (online)

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Gastric cancer associated with pregnancy is extremely rare and the prognosis is generally grave. A 31-year-old Japanese women, 41 weeks pregnant, displayed disseminated intravascular coagulation (DIC), although clinical symptoms and diagnostic examinations did not indicate an obstetrical cause. She went into labor spontaneously and vaginally delivered a 3248-g normal female infant, after receiving a blood transfusion. On the day 5 postpartum, a gastroduodenal fiberscope examination indicated advanced gastric cancer. She was also diagnosed with bilateral chronic subdural hematoma and underwent an operation to allow drainage. It was not possible to treat her curatively, so she was treated conservatively for DIC. She died on day 13 postpartum. Necropsy of the iliac bone indicated bone marrow matastasis of adenocarcinoma. This is the first known case of a pregnant woman with DIC occurring as the first manifestation of advanced gastric cancer.

KEYWORDS

Gastric cancer - pregnancy - disseminated intravascular coagulation

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Takumi KurabayashiM.D. Ph.D. 

Department of Obstetrics and Gynecology, Niigata University School of Medicine

1-757, Asahimachi-dori, Niigata-shi, Niigata 951-8510, Japan