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Synfacts 2005(0): 0004-0004  
DOI: 10.1055/s-2005-865344
Synthesis of Natural Products and Drugs
© Georg Thieme Verlag Stuttgart · New York

Total Synthesis of (+)-Leucascandrolide A

Contributor(s): Philip Kocienski
Q. Su, J. S. Panek*
Boston University, USA
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Publication History

Publication Date:
20 July 2005 (online)

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Significance

Leucascandrolide A (from a calcareous sponge Leucascandra caveolata) is cytotoxic towards various cancer cells and it inhibits the pathogenic yeast Candida albicans. It is probably a metabolite of opportunistic bacteria.