PDF herunterladen
Synfacts 2005(0): 0046-0046  
DOI: 10.1055/s-2005-869911
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart · New York

Selective 1,3-Isomerization of Allylic Alcohols via Rhenium Oxo Catalysis

Contributor(s): Hisashi Yamamoto, Matthew Boxer
C. Morrill, R. H. Grubbs*
California Institute of Technology, Pasadena, USA
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
20. Juli 2005 (online)

   Lizenzen und Reprints

Significance

A protocol featuring mild conditions, short reaction times and low catalyst loading has been developed for the 1,3-isomerization of allylic alcohols using a rhenium oxo catalyst. Enantioenriched starting materials undergo iso­merization with only a small loss of optical purity.