Synfacts 2005(1): 0154-0154  
DOI: 10.1055/s-2005-872129
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart · New York

A New Synthesis of Amides from Imines, Acid Chlorides and Organostannanes

Contributor(s): Paul Knochel, Andrei Gavryushin
D. A. Black, B. A. Arndsten*
McGill University, Montreal, Canada
Further Information

Publication History

Publication Date:
21 September 2005 (online)


This article reports a new Cu-catalyzed three-component reaction, leading to functionalized amides in good yields under very mild conditions. This reaction can be widely applied in the synthesis of biologically relevant molecules.