Synfacts 2005(1): 0157-0157  
DOI: 10.1055/s-2005-872131
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart · New York

Ti-Catalyzed Reductive Coupling of Terpenic Allylic Halides

Contributor(s): Paul Knochel, Andrei Gavryushin
A. F. Barrero*, M. Mar Herrador, J. F. Quílez del Moral, P. Arteaga, J. Arteaga, M. Piedra, E. M. Sánchez
University of Granada, Spain
Further Information

Publication History

Publication Date:
21 September 2005 (online)


A mild procedure for the α,α-homocoupling of allylic halides is applied for the synthesis of various terpene frameworks. A catalytic amount of Cp2TiCl2 and an excess of Mn as a reducing agent are required for this transformation.