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Synfacts 2005(2): 0196-0196  
DOI: 10.1055/s-2005-916048
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York

Synthesis of (+)-Aurilol

Contributor(s): Philip Kocienski
Y. Morimoto*, Y. Nishikawa, M. Takaishi
OSAKA CITY UNIVERSITY, JAPAN
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Publication History

Publication Date:
25 October 2005 (online)

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Significance

(+)-Aurilol is a potent cytotoxic bromotriterpene polyether isolated from the sea hare Dolabella auricularia. The absolute stereochemistry of the target was determined by this total synthesis.