Catalytic Enantioselective Imino-Reformatsky Reaction

P. G. Cozzi

doi:10.1055/s-2006-955713

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Synfacts 2007(1): 0050-0050
DOI: 10.1055/s-2006-955713

Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions

Catalytic Enantioselective Imino-Reformatsky Reaction

Contributor(s): Hisashi Yamamoto, Joshua P. Abell
P. G. Cozzi*
Università Di Bologna, Italy

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Publication History

Publication Date:
15 December 2006 (online)

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Significance

The Reformatsky reaction is widely used in organic synthesis since the subsequent zinc enolate generated can undergo reactions with aldehydes, ketones or imines. This paper describes the first catalytic enantioselective imino-Reformatsky three-component reaction.