Synthesis of (-)-Subincanadine B

K. Suzuki; H. Takayama

doi:10.1055/s-2006-955767

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Synfacts 2007(2): 0131-0131
DOI: 10.1055/s-2006-955767

Synthesis of Natural Products and Potential Drugs

Synthesis of (-)-Subincanadine B

Contributor(s): Philip Kocienski, Zofia Komsta
K. Suzuki, H. Takayama*
Chiba University, Japan

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Publication History

Publication Date:
23 January 2007 (online)

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Significance

The (-)-subincanadines are indole alkaloids isolated from Aspidosperma subincanum. Suzuki and Takayama reported an enantioselective route to (-)-subincanadines A and B utilizing diastereoselective intramolecular Pictet-Spengler and Nozaki-Hiyama-Kishi reactions.