Synfacts 2007(5): 0463-0463  
DOI: 10.1055/s-2007-968399
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York

Synthesis of (+)-Rishirilide B

Contributor(s): Philip Kocienski, Thomas Snaddon
L. H. Mejorado, T. R. R. Pettus*
University of California, Santa Barbara, USA
Further Information

Publication History

Publication Date:
24 April 2007 (online)


(+)-Rishirilide B is a potent inhibitor of α2-macroglobulin, and may find use in the treatment of thrombosis. Key to this synthesis is the oxidative dearomatization of a functionalized ­phenol.