Synfacts 2007(5): 0523-0523  
DOI: 10.1055/s-2007-968424
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart · New York

Unsymmetrical Sulfides, Selenides, and Tellurides from Organoboronic Acids

Contributor(s): Paul Knochel, Andrei Gavryushin
N. Taniguchi*
Fukushima Medical University, Japan
Further Information

Publication History

Publication Date:
24 April 2007 (online)


This procedure allows a convenient and general transformation of various organoboronic acids into unsymmetrical sulfides, selenides, or tellurides. The mild reaction conditions ensure an excellent functional group tolerance, thus making this reaction useful for the combinatorial-like synthesis of biologically relevant molecules. The best yields are achieved with aryl chalcogenides and arylboronic acids; nevertheless, the scope of suitable substrates is quite broad. This is one of few useful methods for the preparation of unsymmetrical selenides and tellurides.