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Preparation and Wittig Reactions of Organotrifluoroborato Phosphonium Ylides
G. A. Molander*, J. Ham, B. Canturk
University of Pennsylvania, Philadelphia, USA and Korea Institute of Science and Technology, Gangneung, Korea
24 April 2007 (online)
This is a new contribution from the group of Molander on the synthetic chemistry of organotrifluoroborates. This method offers a simple way for the synthesis of various functionalized aryltrifluoroborates starting from bench-stable organotrifluoroborato triarylphosphonium reagents. A broad range of aldehydes were successfully utilized in this reaction. A one-pot protocol for the alkene synthesis starting from the corresponding benzyl chlorides has also been reported.