Synthesis of Jerangolid D

J. Pospísil; I. E. Markó

doi:10.1055/s-2007-968713

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Synfacts 2007(8): 0790-0790
DOI: 10.1055/s-2007-968713

Synthesis of Natural Products and Potential Drugs

Synthesis of Jerangolid D

Contributor(s): Philip Kocienski, Fiona Black
J. Pospísil, I. E. Markó*
Université Catholique de Louvain, Belgium

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Publication History

Publication Date:
24 July 2007 (online)

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Significance

Jerangolid D is a potential antifungal agent isolated from the myxobacterium Sorangium cellulosum. A convergent synthesis of Jerangolid D is reported in which the three fragments are linked using a Julia olefination and a Julia-Kocienski reaction.