Subscribe to RSS
Titanium-Promoted Cross-Coupling of Substituted Olefins and Imines
M. Takahashi, G. C. Micalizio*
Yale University, New Haven, USA
23 August 2007 (online)
A Ti-mediated regio- and stereoselective cross-coupling of substituted olefins and imines is reported for achiral and chiral homoallylic alcohols and achiral and chiral imines, providing a convenient route to 1,5-amino alcohols which can cyclize to form piperidines.