Plötzlicher, unerwarteter Tod bei Epilepsie (SUDEP): Aktueller Wissensstand und Konsequenzen für die Information von Patienten und Angehörigen

Zusammenfassung

Das derzeitige Wissen über den plötzlichen ungeklärten bzw. unerwarteten Tod bei Epilepsie (englisch: sudden unexplained/unexpected death in patients with epilepsy; SUDEP) wird zusammengefasst. Bei schwer behandelbaren vermutlich symptomatischen („kryptogenen”) und symptomatischen Epilepsien mit fokal beginnenden Anfällen muss davon ausgegangen werden, dass mindestens jeder zweite vorzeitige Todesfall einem SUDEP entspricht. Es werden Anregungen für die Information von speziell Hochrisiko-Patienten und deren Angehörigen gegeben.

Abstract

The current knowledge of sudden unexplained/unexpected death in patients with epilepsy or SUDEP is summarized. In pharmacorefractory presumably symptomatic („cryptogenic”) and symptomatic epilepsies with focal onset seizures it has to be assumed that more than 50 % of early deaths are SUDEP. Suggestions for the information of especially high risk patients and their relatives are made.

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